Transperineal, MRI-guided, Prostate Biopsy

Primary purpose: Complications and rehospitalizations after transperineal prostate biopsy MRI-guided are reduced than transrectal prostate biopsies. Secondary purposes: Patients tolerance after transperineal prostate biopsy MRI-guided is better than after transrectal prostate biopsies. Core of transperineal prostate biopsies are better than core of transrectal prostate biopsies Study of correlation between radiologic images and anatomopathologic result Description of needle track during the procedure Description of real time template saturation prostate biopsy Comparison of transperineal prostate biopsy relevance according to EBM Comparison of 1.5T MRI and 3T MRI for prostate cancer detection

Inclusion criteria: Men 40 to 80 years' old Affiliation to French social health system Signed consent Prostate cancer suspicion based on prostate specific antigen (PSA) or digital rectal exam WITH abnormal MRI (Prostate Imaging Reporting and Data System score 3) AND negative transrectal prostate biopsies Patient treated by active surveillance for a low risk prostate cancer (T1c or T2a, Gleason = 6, PSA < 10) Exclusion criteria: Gleason > 6 prostate cancer Metastatic prostate cancer Contraindication to MRI Contraindication to general anesthesia Non-reversible hemostasis trouble Inability to give consent