Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
Intracranial Aneurysm, Brain Edema, Scoliosis
About this trial
This is an interventional treatment trial for Intracranial Aneurysm
Eligibility Criteria
Inclusion Criteria:
- Neurosurgical patients with concerns for decreased intracranial compliance;
- Orthopedic spine patients;
- Patients scheduled to undergo neurosurgical interventions that include any of the following will be eligible: intracranial aneurysm repair; or, major spine surgery.
Exclusion Criteria:
- Patients with permanent cardiac arrhythmias;
- Patients with severe aortic regurgitation;
- Patients with intra-aortic balloon pump (IABP);
- Patients undergoing emergency surgery; and,
- Women who are pregnant and/or nursing will be excluded.
Sites / Locations
- New York University School of Medicine
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Goal Directed Therapy
Control Group
Flotrack monitor is connected and based on what anesthesiologist sees and following study algorithm, anesthesiologist chooses: Phenylephrine, Epinephrine , volume resuscitation (fluids, including normal saline, albumin, voluven and packed red blood cells) and no intervention.
FloTrac monitor is connected, but he anesthesiologist will not be able to see the monitor although the data will be collected and stored for analysis. Anesthesiologist will be given a study algorithm to follow for the duration of the surgery, and based on it will choose: Phenylephrine, Epinephrine , volume resuscitation (fluids, including normal saline, albumin, voluven and packed red blood cells) and no intervention.