Transcranial Random Noise Stimulation in Food Addiction Treatment (tRNS-FA)
Overweight, Obesity and Other Hyperalimentation (E65-E68)
About this trial
This is an interventional treatment trial for Overweight, Obesity and Other Hyperalimentation (E65-E68) focused on measuring tRNS, Food addiction,, Obesity, Craving, functional magnetic resonance imaging (fMRI)
Eligibility Criteria
Inclusion Criteria:
- Female or male between 18 and 65 years old
- Patients suffering from obesity, with a BMI ≥ 30.
- Food dependence score at the Yale Food addiction Scale ≥ 3
Exclusion Criteria:
- Presence of a an other psychiatric diagnosis of Axis I (DSM IV);
- Presence of addictive comorbidity other than food addiction
- Psychotropic treatment;
- Pregnancy or lactation;
- Contraindication to fMRI .
Sites / Locations
- Centre Hospitalier Le Vinatier
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
Active tRNS treatment
Placebo tRNS treatment
The intervention consists in active tRNS stimulation with cathode above the left dorsolateral prefrontal cortex (DLPFC) which corresponds to the F3 location given by the 10-20 system. Anode is above the right dorsalateral prefrontal cortex (F4). 100 (Hertz)Hz-650Hz, 2milliampere(mA), 30min, twice daily, 5 days
The intervention consists in placebo or sham tRNS stimulation electrode are above F3 and F4. Voltage will be ramped at the begin and end of a stimulation for 30 seconds. Placebo stimulation will consist of just applying the ramps at the begin and end of the stimulation.