Does Cognitive Impairment Affect Rehabilitation Outcome in Parkinson's Disease?
Parkinson's Disease
About this trial
This is an interventional treatment trial for Parkinson's Disease focused on measuring Cognition Impairment, Rehabilitation, Parkinson's Disease
Eligibility Criteria
Inclusion Criteria:
- Parkinsonian patients according to the UK Brain Bank criteria
Exclusion Criteria:
- Major stroke, possible hydrocephalus or brain tumor observed on CT scan or brain MRI
- Major depression, active psychosis or clinically significant psychiatric disorders
- Visual or auditory disturbances that prevent the neuropsychological assessment
- The increase in drug dosage during hospitalization
Sites / Locations
- Department of Parkinson's Disease and Brain Injury Rehabilitation, of the 'Moriggia-Pelascini' Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Experimental
Experimental
Experimental
Experimental
Experimental
normal cognition
mildly impaired cognition
moderately-severely impaired cognition
patients with normal executive functions
pathological executive functions
Group 1: patients with normal cognitive profile, assessed with MMSE (27 ≤ correct score ≤ 30) undergoing MIRT
Group 3: patients with middle cognitive decline, assessed with MMSE (20 ≤ correct score < 27) undergoing MIRT
Group 2: patients cognitive decline, assessed with MMSE (correct score < 20) undergoing MIRT
Group 4: patients with pathological executive functions, assessed with FAB (FAB ≥ 13.8) undergoing MIRT
Group 5: patients with pathological executive functions, assessed with FAB (FAB < 13.8) undergoing MIRT