Back to resultsEffects of Berry Nectars Sweetened With Inverted Sugar on Post-meal Blood Sugar
Primary Purpose
Hyperglycemia, Postprandial
Status
Completed
Phase
Not Applicable
Locations
Finland
Study Type
Interventional
Intervention
Blackcurrant Nectar
Lingonberry Nectar
Reference
Sponsored by
About this trial
This is an interventional basic science trial for Hyperglycemia, Postprandial focused on measuring Berries, Blackcurrant (Ribes nigrum), Lingonberry (Vaccinium vitis-idaea), Sucrose, Inverted sugar, Postprandial glucose response, Postprandial insulin response
Eligibility Criteria
Inclusion Criteria:
- BMI 20-28 kg/m2
- Normal fasting plasma glucose
Exclusion Criteria:
- Smoking
- Diabetes or other chronic disease
- Antibiotic medication within the past 3 months
- Blood donation within the past month
Sites / Locations
- University of Eastern Finland
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm Type
Experimental
Experimental
Active Comparator
Arm Label
Blackcurrant nectar
Lingonberry nectar
Reference
Arm Description
Contains 17.5 g glucose and 17.5 g fructose representing 35 g completely inverted sucrose
Contains 17.5 g glucose and 17.5 g fructose representing 35 g completely inverted sucrose
Sugar control, contains 17.5 g glucose and 17.5 g fructose in water
Outcomes
Primary Outcome Measures
Plasma glucose response
0, 15, 30, 45, 60, 90, 120 minutes post-meal
Secondary Outcome Measures
Plasma insulin response
0, 15, 30, 45, 60, 90, 120 minutes post-meal
Full Information
NCT ID
NCT02743130
First Posted
April 14, 2016
Last Updated
April 14, 2016
Sponsor
University of Eastern Finland
Collaborators
Finnsugar Ltd
1. Study Identification
Unique Protocol Identification Number
NCT02743130
Brief Title
Effects of Berry Nectars Sweetened With Inverted Sugar on Post-meal Blood Sugar
Official Title
Postprandial Glycemic Response to Berry Nectars Containing Inverted Sugar
Study Type
Interventional
2. Study Status
Record Verification Date
April 2016
Overall Recruitment Status
Completed
Study Start Date
September 2014 (undefined)
Primary Completion Date
November 2014 (Actual)
Study Completion Date
November 2014 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Eastern Finland
Collaborators
Finnsugar Ltd
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Berries have been shown to improve postprandial glucose and insulin responses to sucrose. During processing and storage of berry products, sucrose is inverted to glucose and fructose. The effects of berries on the glycemic response induced by inverted sugar are not known. The purpose of this study is to determine whether berries are effective in lowering the postprandial glucose and insulin responses induced by inverted sugar.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hyperglycemia, Postprandial
Keywords
Berries, Blackcurrant (Ribes nigrum), Lingonberry (Vaccinium vitis-idaea), Sucrose, Inverted sugar, Postprandial glucose response, Postprandial insulin response
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Masking
Investigator
Allocation
Randomized
Enrollment
18 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Blackcurrant nectar
Arm Type
Experimental
Arm Description
Contains 17.5 g glucose and 17.5 g fructose representing 35 g completely inverted sucrose
Arm Title
Lingonberry nectar
Arm Type
Experimental
Arm Description
Contains 17.5 g glucose and 17.5 g fructose representing 35 g completely inverted sucrose
Arm Title
Reference
Arm Type
Active Comparator
Arm Description
Sugar control, contains 17.5 g glucose and 17.5 g fructose in water
Intervention Type
Dietary Supplement
Intervention Name(s)
Blackcurrant Nectar
Intervention Description
Consumption of a single dose (300 ml)
Intervention Type
Dietary Supplement
Intervention Name(s)
Lingonberry Nectar
Intervention Description
Consumption of a single dose (300 ml)
Intervention Type
Dietary Supplement
Intervention Name(s)
Reference
Intervention Description
Consumption of a single dose (300 ml)
Primary Outcome Measure Information:
Title
Plasma glucose response
Description
0, 15, 30, 45, 60, 90, 120 minutes post-meal
Time Frame
2 hours
Secondary Outcome Measure Information:
Title
Plasma insulin response
Description
0, 15, 30, 45, 60, 90, 120 minutes post-meal
Time Frame
2 hours
10. Eligibility
Sex
All
Minimum Age & Unit of Time
25 Years
Maximum Age & Unit of Time
69 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
BMI 20-28 kg/m2
Normal fasting plasma glucose
Exclusion Criteria:
Smoking
Diabetes or other chronic disease
Antibiotic medication within the past 3 months
Blood donation within the past month
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Riitta Törrönen, Dr
Organizational Affiliation
Senior Scientist
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Eastern Finland
City
Kuopio
ZIP/Postal Code
FI-70211
Country
Finland
12. IPD Sharing Statement
Plan to Share IPD
No
Learn more about this trial
Effects of Berry Nectars Sweetened With Inverted Sugar on Post-meal Blood Sugar
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