Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training
Primary Purpose
Memory Deficits
Status
Completed
Phase
Not Applicable
Locations
Germany
Study Type
Interventional
Intervention
Standard Therapy
Experimental Intervention
Sponsored by
About this trial
This is an interventional treatment trial for Memory Deficits focused on measuring working memory, recollection training, transfer
Eligibility Criteria
Inclusion Criteria:
- brain injury
- memory deficits (performance below average in the California Verbal Learning Test in learning trial 1 or 5, sfr or lfr)
Exclusion Criteria:
- severe amnesia (less than 2 words in sfr of the CVLT), dementia, sensory or motor aphasia, impaired vision, insufficient German language skills, lack of patient's consent
Sites / Locations
- Rehabilitationszentrum GmbH
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Experimental
Arm Label
Standard Therapy
Experimental Intervention
Arm Description
Learning and practicing memory strategies
Computerbased working memory training and Recollection training
Outcomes
Primary Outcome Measures
Test to assess change in memory performance in everyday life
The test includes different single tasks that measure memory in everyday life e.g. Story recall (Subtest 6 from the Rivermead Behavioral Memory Test) Outcome measure: Total number of points
Secondary Outcome Measures
Outcome change in different neuropsychological tests
Tests for verbal memory, working memory, prospective memory, attention and word fluency (Composite scores built from raw scores)
Full Information
NCT ID
NCT02790151
First Posted
March 2, 2015
Last Updated
October 17, 2016
Sponsor
University of Oldenburg
1. Study Identification
Unique Protocol Identification Number
NCT02790151
Brief Title
Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training
Official Title
Memory Rehabilitation by Means of Working Memory Training in Combination
Study Type
Interventional
2. Study Status
Record Verification Date
October 2016
Overall Recruitment Status
Completed
Study Start Date
November 2014 (undefined)
Primary Completion Date
October 2016 (Actual)
Study Completion Date
October 2016 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Oldenburg
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Memory deficits after brain damage are common and there is still a need for evaluated therapy methods. In this study we compare two therapeutic interventions and investigate whether therapy effects can be found on neuropsychological tests and on a test measuring memory in everyday life.
Detailed Description
In the interventiongroup a computerbased working memory training is combined with a recollection training (repitition-lag procedure). The patients in the active control group undergo the standard memory therapy that is normally provided in the rehabilitation centre (with a focus on the acquisition and execution of different memory strategies, e.g. the spaced retrieval method). The patients in both groups are tested on different neuropsychological tests before and after nine hours of therapy. Additionally, a test is conducted that assesses memory in everyday life.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Memory Deficits
Keywords
working memory, recollection training, transfer
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
36 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Standard Therapy
Arm Type
Active Comparator
Arm Description
Learning and practicing memory strategies
Arm Title
Experimental Intervention
Arm Type
Experimental
Arm Description
Computerbased working memory training and Recollection training
Intervention Type
Behavioral
Intervention Name(s)
Standard Therapy
Intervention Description
Learning and practicing Memory strategies
Intervention Type
Behavioral
Intervention Name(s)
Experimental Intervention
Intervention Description
Computerbased Working Memory Training in Combination with a Recollection Training
Primary Outcome Measure Information:
Title
Test to assess change in memory performance in everyday life
Description
The test includes different single tasks that measure memory in everyday life e.g. Story recall (Subtest 6 from the Rivermead Behavioral Memory Test) Outcome measure: Total number of points
Time Frame
baseline and 9 hours
Secondary Outcome Measure Information:
Title
Outcome change in different neuropsychological tests
Description
Tests for verbal memory, working memory, prospective memory, attention and word fluency (Composite scores built from raw scores)
Time Frame
baseline and 9 hours
10. Eligibility
Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
brain injury
memory deficits (performance below average in the California Verbal Learning Test in learning trial 1 or 5, sfr or lfr)
Exclusion Criteria:
severe amnesia (less than 2 words in sfr of the CVLT), dementia, sensory or motor aphasia, impaired vision, insufficient German language skills, lack of patient's consent
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Helmut Hildebrandt, Prof. Dr.
Organizational Affiliation
Universität Oldenburg
Official's Role
Study Director
Facility Information:
Facility Name
Rehabilitationszentrum GmbH
City
Oldenburg
State/Province
Deutschland
ZIP/Postal Code
26131
Country
Germany
12. IPD Sharing Statement
Citations:
PubMed Identifier
29697993
Citation
Richter KM, Modden C, Eling P, Hildebrandt H. Improving everyday memory performance after acquired brain injury: An RCT on recollection and working memory training. Neuropsychology. 2018 Jul;32(5):586-596. doi: 10.1037/neu0000445. Epub 2018 Apr 26.
Results Reference
derived
Learn more about this trial
Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training
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