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Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training

Primary Purpose

Memory Deficits

Status
Completed
Phase
Not Applicable
Locations
Germany
Study Type
Interventional
Intervention
Standard Therapy
Experimental Intervention
Sponsored by
University of Oldenburg
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Memory Deficits focused on measuring working memory, recollection training, transfer

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • brain injury
  • memory deficits (performance below average in the California Verbal Learning Test in learning trial 1 or 5, sfr or lfr)

Exclusion Criteria:

  • severe amnesia (less than 2 words in sfr of the CVLT), dementia, sensory or motor aphasia, impaired vision, insufficient German language skills, lack of patient's consent

Sites / Locations

  • Rehabilitationszentrum GmbH

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Experimental

Arm Label

Standard Therapy

Experimental Intervention

Arm Description

Learning and practicing memory strategies

Computerbased working memory training and Recollection training

Outcomes

Primary Outcome Measures

Test to assess change in memory performance in everyday life
The test includes different single tasks that measure memory in everyday life e.g. Story recall (Subtest 6 from the Rivermead Behavioral Memory Test) Outcome measure: Total number of points

Secondary Outcome Measures

Outcome change in different neuropsychological tests
Tests for verbal memory, working memory, prospective memory, attention and word fluency (Composite scores built from raw scores)

Full Information

First Posted
March 2, 2015
Last Updated
October 17, 2016
Sponsor
University of Oldenburg
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1. Study Identification

Unique Protocol Identification Number
NCT02790151
Brief Title
Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training
Official Title
Memory Rehabilitation by Means of Working Memory Training in Combination
Study Type
Interventional

2. Study Status

Record Verification Date
October 2016
Overall Recruitment Status
Completed
Study Start Date
November 2014 (undefined)
Primary Completion Date
October 2016 (Actual)
Study Completion Date
October 2016 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Oldenburg

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Memory deficits after brain damage are common and there is still a need for evaluated therapy methods. In this study we compare two therapeutic interventions and investigate whether therapy effects can be found on neuropsychological tests and on a test measuring memory in everyday life.
Detailed Description
In the interventiongroup a computerbased working memory training is combined with a recollection training (repitition-lag procedure). The patients in the active control group undergo the standard memory therapy that is normally provided in the rehabilitation centre (with a focus on the acquisition and execution of different memory strategies, e.g. the spaced retrieval method). The patients in both groups are tested on different neuropsychological tests before and after nine hours of therapy. Additionally, a test is conducted that assesses memory in everyday life.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Memory Deficits
Keywords
working memory, recollection training, transfer

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
36 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Standard Therapy
Arm Type
Active Comparator
Arm Description
Learning and practicing memory strategies
Arm Title
Experimental Intervention
Arm Type
Experimental
Arm Description
Computerbased working memory training and Recollection training
Intervention Type
Behavioral
Intervention Name(s)
Standard Therapy
Intervention Description
Learning and practicing Memory strategies
Intervention Type
Behavioral
Intervention Name(s)
Experimental Intervention
Intervention Description
Computerbased Working Memory Training in Combination with a Recollection Training
Primary Outcome Measure Information:
Title
Test to assess change in memory performance in everyday life
Description
The test includes different single tasks that measure memory in everyday life e.g. Story recall (Subtest 6 from the Rivermead Behavioral Memory Test) Outcome measure: Total number of points
Time Frame
baseline and 9 hours
Secondary Outcome Measure Information:
Title
Outcome change in different neuropsychological tests
Description
Tests for verbal memory, working memory, prospective memory, attention and word fluency (Composite scores built from raw scores)
Time Frame
baseline and 9 hours

10. Eligibility

Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: brain injury memory deficits (performance below average in the California Verbal Learning Test in learning trial 1 or 5, sfr or lfr) Exclusion Criteria: severe amnesia (less than 2 words in sfr of the CVLT), dementia, sensory or motor aphasia, impaired vision, insufficient German language skills, lack of patient's consent
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Helmut Hildebrandt, Prof. Dr.
Organizational Affiliation
Universität Oldenburg
Official's Role
Study Director
Facility Information:
Facility Name
Rehabilitationszentrum GmbH
City
Oldenburg
State/Province
Deutschland
ZIP/Postal Code
26131
Country
Germany

12. IPD Sharing Statement

Citations:
PubMed Identifier
29697993
Citation
Richter KM, Modden C, Eling P, Hildebrandt H. Improving everyday memory performance after acquired brain injury: An RCT on recollection and working memory training. Neuropsychology. 2018 Jul;32(5):586-596. doi: 10.1037/neu0000445. Epub 2018 Apr 26.
Results Reference
derived

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Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training

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