Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation (NLP)

This is an interventional prevention trial for Immune System and Related Disorders Read More

Inclusion Criteria:

Must:

1. Be Active Duty Service Members.
2. at least 18 years of age or older.
3. Be requiring and eligible for inactivated influenza vaccine receipt.
4. Be willing and able to complete the study protocol requirements.
5. Have a current Flu Screening Form with medical clearance to receive the influenza vaccination.

Exclusion Criteria:

Must Not:

1. Have already received influenza vaccine for the current season.
2. Have received any type of vaccine in the previous 72 hours.
3. Be on a medical profile resulting in current profile exemption from Physical Training of Upper 2 or Upper 3. (Upper extremity injury or illness)
4. Have preexisting symptoms of injury or infection or other local symptoms that would interfere with site assessment.
5. Be pregnant.
6. Have a history of allergy, intolerance, stomach bleeding or other medical exclusion for ibuprofen.
7. Have a history of stroke or coronary artery disease, such as uncontrolled high blood pressure or abnormal heart beat.
8. Has taken any topical or oral pain medications from the following medication classes in the past 24 hours prior to the start of the study: oral acetaminophen, opioids, tramadol, nonsteroidal anti-inflammatory drug (NSAID) or acetylsalicylic acid (ASA) or topical pain relievers or counterirritants of menthol, methyl salicylate, camphor menthols, and capsaicins.
9. Have any chronic or acute illness or treatment causing immunological suppression such as current oral steroid therapy, malignancy or chemotherapy or lung disease. (not including controlled asthma)

10. Currently participating in any other study

    -