FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis
Periodontitis, Type 2 Diabetes Mellitus
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring Diabetes, Oral Hygiene, Periodontal Surgery, Periodontal Medicine
Eligibility Criteria
Inclusion Criteria:
- Diagnosed with type 2 Diabetes Mellitus; having a baseline HbA1c ≥ 6.5%, at least 10 teeth in the functional dentition (excluding third molars) and a clinical diagnosis of periodontal disease with at least one site with probing depth (PD) ≥ 5mm, and two teeth with attachment lost ≥ 6mm and no modification in the pharmacological treatment of diabetes during the study period.
Exclusion Criteria:
- Pregnancy or lactation, major diabetic complications, uses of antibiotic therapy or non-steroidal anti-inflammatory drug therapy 4 months before the first visit.
Sites / Locations
- Oral Surgery, Dental Polyclinic (HUCSK)Recruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Surgical periodontal treatment
Surgical and non-surgical periodontal treatment
Type 2 Diabetes Patients with periodontitis (without initial non-surgical periodontal therapy) at least one tooth extraction will be performed. Non-Diabetes Patients with periodontitis (without initial non-surgical periodontal therapy) at least one tooth extraction will be performed. Intervention: Procedure: Surgery (Tooth Extraction)
Type 2 Diabetes Patients with periodontitis (with initial non-surgical periodontal therapy) at least one tooth extraction will be performed. Non-Diabetes Patients with periodontitis (with initial non-surgical periodontal therapy) at least one tooth extraction will be performed. Interventions: Procedure: Surgery (Tooth Extraction) Procedure: Non-surgical periodontal therapy-full mouth scaling and root planing (FM-SRP) with ultrasonic device and periodontal curets for mechanical debridement of the supra- and sub-gingival plaque and calculus, post operative rinsing thrice a day for 3 weeks.