Back to resultsPhysiological Characteristics of High Altitude Climbers (ALTIPERF)
Primary Purpose
Hypoxia, Exercise, Sport Performance
Status
Completed
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
Stress test
Sponsored by
About this trial
This is an interventional health services research trial for Hypoxia focused on measuring elite climbers, near infrared spectroscopy
Eligibility Criteria
Inclusion Criteria:
- Age between 18 and 40
- Member of the national high altitude climbing group
Exclusion Criteria:
- Any diseases incompatible with hypoxic exposure, exercise testing
- Pregnancy
Sites / Locations
- Grenoble University Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Other
Other
Arm Label
Elite climbers
Sea level sportsmen
Arm Description
Elite climbers selected in a national group for their previous performances at high altitude
Control group with similar anthropometric, age, gender and maximal normoxic oxygen consumption that the elite climber group
Outcomes
Primary Outcome Measures
Performance reduction in hypoxia versus normoxia
Difference in maximal cycling power output between the normoxic and the hypoxic exercise test
Secondary Outcome Measures
Near infrared signals during exercise
Differences in cerebral and muscle TOI during exercise between the normoxia and the hypoxic exercise
Full Information
NCT ID
NCT02880150
First Posted
October 21, 2013
Last Updated
August 22, 2016
Sponsor
University Hospital, Grenoble
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
1. Study Identification
Unique Protocol Identification Number
NCT02880150
Brief Title
Physiological Characteristics of High Altitude Climbers
Acronym
ALTIPERF
Official Title
Physiological Characteristics of High Altitude Climbers
Study Type
Interventional
2. Study Status
Record Verification Date
August 2016
Overall Recruitment Status
Completed
Study Start Date
May 2013 (undefined)
Primary Completion Date
March 2014 (Actual)
Study Completion Date
May 2014 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University Hospital, Grenoble
Collaborators
Institut National de la Santé Et de la Recherche Médicale, France
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Climbing at high altitude and tolerating hypoxic environment require specific physiological adaptations. Large intersubjects differences exist regarding the ability to adapt to high altitude and hypoxia. The present study aims to characterise the physiological responses to hypoxia in a group of elite climbers by comparison to sea level athletes. We hypothesised that elite climbers would show better physiological responses to hypoxia and more preserved performances compared to sea level.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hypoxia, Exercise, Sport Performance
Keywords
elite climbers, near infrared spectroscopy
7. Study Design
Primary Purpose
Health Services Research
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
20 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Elite climbers
Arm Type
Other
Arm Description
Elite climbers selected in a national group for their previous performances at high altitude
Arm Title
Sea level sportsmen
Arm Type
Other
Arm Description
Control group with similar anthropometric, age, gender and maximal normoxic oxygen consumption that the elite climber group
Intervention Type
Other
Intervention Name(s)
Stress test
Primary Outcome Measure Information:
Title
Performance reduction in hypoxia versus normoxia
Description
Difference in maximal cycling power output between the normoxic and the hypoxic exercise test
Time Frame
Day one on the evaluation day
Secondary Outcome Measure Information:
Title
Near infrared signals during exercise
Description
Differences in cerebral and muscle TOI during exercise between the normoxia and the hypoxic exercise
Time Frame
Day one on the evaluation day
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
40 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Age between 18 and 40
Member of the national high altitude climbing group
Exclusion Criteria:
Any diseases incompatible with hypoxic exposure, exercise testing
Pregnancy
Facility Information:
Facility Name
Grenoble University Hospital
City
Grenoble
ZIP/Postal Code
38042
Country
France
12. IPD Sharing Statement
Citations:
PubMed Identifier
22319046
Citation
Verges S, Rupp T, Jubeau M, Wuyam B, Esteve F, Levy P, Perrey S, Millet GY. Cerebral perturbations during exercise in hypoxia. Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R903-16. doi: 10.1152/ajpregu.00555.2011. Epub 2012 Feb 8.
Results Reference
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Physiological Characteristics of High Altitude Climbers
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