Essential Oil+ELA, Plaque and Gingivitis
Dental Plaque, Gingivitis
About this trial
This is an interventional prevention trial for Dental Plaque
Eligibility Criteria
Inclusion Criteria:
healthy subjects from both gender snon-smoking aged 20-55yr having at least three of the following teeth in maxillary right and left quadrant: the canine, 1st bicuspid, 2nd bicuspid, 1st molar, healthy gingiva and periodontium.
Exclusion Criteria:
pregnancy lactation any chronic diseases clinical signs or symptoms of acute infection in the oral cavity any prescribed or non-prescription systemic or topical medication except oral contraceptives clinical parameters judged as unacceptable by the principle investigator use of systemic antibiotics the last 3 months prior to the start of the study history of alcohol or drug abuse participation in other clinical studies in the last 4weeks
Sites / Locations
- Department of Periodontology, Institute of Clinical Odontology, Dental Faculty, University of Oslo
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Placebo Comparator
Sham Comparator
Listerine prof.gum.ther
21.6% hydroalcoholic
Plain sterile water
The test solution was the commercially available mouthwash product EOELA that contains essential oils and ELA in 21.6% alcohol (Listerine Professional Gum Therapy®, Johnson & Johnson,USA). Intervention; Rinsing 30 sec with test solution twice daily for 21 days
a hydro-alcohol solution made from 96% ethanol diluted with sterilized water to the final concentration of 21.6%. Intervention: Rinsing 30 sec with placebo comparator twice daily for 21 days
Plain sterile water. Intervention: Rinsing 30 sec with sham comparator twice daily for 21 days