Multicolour Versus Monocolour Specimens Inking After Pancreaticoduodenectomy for Periampullary Cancer (MPM)
Stage, Pancreatic Cancer, Neoplasm, Residual, Pancreatic Neoplasm
About this trial
This is an interventional diagnostic trial for Stage, Pancreatic Cancer focused on measuring cancer, resection margin, pathology, pancreas
Eligibility Criteria
Inclusion Criteria:
- medical history without previous pancreatic resection or pancreatic cancer
- written consent
Exclusion Criteria:
- patients previously treated with chemotherapy radiotherapy or chemoradiotherapy for pancreatic cancer
- patients with diagnostic doubts of chronic pancreatitis, serous cystic tumours, intraductal papillary mucinous tumours or neuroendocrine tumours
- patients unresectable at laparotomy
- patients who had undergone other pancreatic resections (total or subtotal pancreatectomy).
Sites / Locations
- S.Orsola-Malpighi Hospital, University of Bologna
Arms of the Study
Arm 1
Arm 2
Experimental
Other
Arm A-Multicolour inking specimen
Arm B-Monocolour inking specimen
After performing the pancreaticoduodenectomies, the surgeon intraoperatively inked the surfaces/margins of the specimen with different colours. The surfaces/margins inked were the following: Anterior surface of the pancreas (yellow); Posterior surface of the pancreas (orange); Superior mesenteric/portal vein groove (blu); Superior mesenteric artery margin (retroperitoneal margin) (red); Transection margin of the bile duct (green) The trans-section pancreatic and gastric margins were not inked.
In arm B, only the superior mesenteric artery margin and the pancreatic margin were intraoperatively indicated by the surgeon in the specimen: a single stitch to identify the transection pancreatic margin and a continuous suture to identify the superior mesenteric artery margin. Monochromatic inking of the superior mesenteric artery margin was subsequently carried out by the pathologist.