A "Less-rapid" Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the "Duration of Apnea Without Desaturation" in Paralyzed Non-obese and Morbidly Obese Patients?
Apneic Oxygenation
About this trial
This is an interventional treatment trial for Apneic Oxygenation
Eligibility Criteria
Inclusion Criteria:
- Female patients,
- American Society of Anesthesiologists Rating 1-2,
- Aged 18 through 65 years of age
- Elective gynecological surgery via an abdominal approach (laparoscopic or open)
- Already consented to general anesthesia necessitating endotracheal intubation.
- Are candidates for anesthesia using laryngeal mask airway if needed
Exclusion Criteria:
- Patient refusal to enter study
- History of difficult mask ventilation
- History of, or anticipated difficult intubation
- Heavy Smokers (> 10 cigarettes per day)
- Asthma
- Chronic Obstructive Pulmonary Disease
- Heart Disease
- Renal or Liver disease
- Neurological disease.
- Women scored at ≥ 3/4 on the modified Mallampati scale 30.
- Women exhibiting other signs of a potential difficult intubation (limited neck flexion or extension; neck circumference > 30 cm; prominent incisors)
- Patients with a baseline resting oxygenation level of less than 95%.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Other
Experimental
Other
Non-Obese: Apneic Oxygenation: eight minute
Non-Obese: Without Apneic Oxygenation
Obese: Apneic Oxygenation: five minute
Obese: Without Apneic Oxygenation
Non-obese healthy female patients requiring endotracheal anesthesia for gynecologic (open or laparoscopic) abdominal surgery will have the Pentax AWSTM video laryngoscope with attached P blade placed and then receive 10 l/minute flow of oxygen through the P blade (apneic oxygenation) for eight minutes, or earlier if SpO2 falls to ≤ 95%. The trachea will then be intubated and the ventilation of the lungs will commence using 100% oxygen until SpO2 ≥ 98%.
Non-obese healthy female patients requiring endotracheal anesthesia for gynecologic (open or laparoscopic) abdominal surgery will have the Pentax AWSTM video laryngoscope with attached P blade placed for eight minutes, or earlier if SpO2 falls to ≤ 95%. The trachea will then be intubated and the ventilation of the lungs will commence using 100% oxygen until SpO2 ≥ 98%.
Morbidly obese patients (BM I ≥ 40 kg/m2) requiring endotracheal anesthesia for gynecologic (open or laparoscopic) abdominal surgery will have the Pentax AWSTM video laryngoscope with attached P blade placed and then receive 10 l/minute flow of oxygen through the P blade (apneic oxygenation) for five minutes, or earlier if SpO2 falls to ≤ 95%. The trachea will then be intubated and the ventilation of the lungs will commence using 100% oxygen until SpO2 ≥ 98%.
Morbidly obese patients (BM I ≥ 40 kg/m2) requiring endotracheal anesthesia for gynecologic (open or laparoscopic) abdominal surgery will have the Pentax AWSTM video laryngoscope with attached P blade placed for five minutes, or earlier if SpO2 falls to ≤ 95%. The trachea will then be intubated and the ventilation of the lungs will commence using 100% oxygen until SpO2 ≥ 98%.