Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic Disorder (TRACT-RCT)
Depression, Unipolar, Anxiety Disorder Social, Panic Disorder
About this trial
This is an interventional treatment trial for Depression, Unipolar focused on measuring Cognitive Behavior Therapy, Negative Affect, Unified Protocol, Session Tracking, Mechanisms of Change in Psychotherapy
Eligibility Criteria
Inclusion Criteria:
Referred to Danish Mental Health Service
- a principal DSM-5 diagnosis of Unipolar Depression (single episode or recurrent)(app. 50%), Social Anxiety Disorder (app. 25%), and Agoraphobia/Panic Disorder (app 25%)
- the patient is currently not using any antidepressants or use accepted antidepressants (according to predefined list), which have been unchanged for at least 4 weeks before inclusion and no change in antidepressants is anticipated,
- sufficient knowledge of the Danish language.
Exclusion Criteria:
- risk of suicide is high according to clinicians or assessment researchers
- alcohol or drug dependence,
- cluster A or B (DSM-5) personality disorder diagnosed by intake clinicians or assessment researcher,
- co-morbidity of pervasive developmental disorder, psychotic disorders, eating disorders, bipolar disorder, or severe physical illness,
- psychopharmacological treatment other than those predefined as acceptable,
- patient does not accept to stop the use of anxiolytics within the first four weeks of intervention.
Sites / Locations
- Psychotherapeutic Unit, Mental Health Centre Copenhagen
- Outpatient Clinic for Anxiety and Personality Disorders
- Outpatient Clinic for Mania and Depression
- Psychiatric Outpatient Clinic
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
UP-CBT
Standard-CBT
The "Unified Protocol for Transdiagnostic Treatment of Emotional Disorders" (UP) is one of the most widely studied transdiagnostic manuals. Here, the investigators apply a group manual that has been modified from the published UP for individual therapy based on recommendations on group delivery from the UP Institute (personal communications) and integrations modifications necessary for the delivery in the Mental Health Service. Group UP-CBT, consist of 8 treatment modules delivered in 14 group sessions given weekly in 2 hour sessions.
Group CBT following Danish versions of diagnosis specific manuals (Social Anxiety Disorder (SAD) Group; Depression (DEP) Group; Agoraphobia/Panic Disorder (Ag/PD) (standard-CBT). The original elements of psychoeducation, cognitive restructuring, and exposure/activity scheduling are present in the applied manuals. Standard-CBT, consist of 8 treatment modules delivered in 14 group sessions given weekly in 2 hour sessions.