Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth
Necrotic Pulp
About this trial
This is an interventional treatment trial for Necrotic Pulp focused on measuring Calcium hydroxide intracanal medication, Ca(OH)2 intracanal medication, Chlorhexidene gel, CHX gel, Root canal treatment
Eligibility Criteria
Inclusion Criteria:
- Patients in Good Health(American Society Of Anaesthesiology Class II or higher).
- Adult patients from both genders older than 18-50 years old suffering from chronic periapical periodontitis with necrotic pulp.
- single rooted teeth (maxillary and mandibular).
- Patients who can understand numerical rating scale (NRS)
- Patients able to sign informed consent
Exclusion Criteria:
- Patients with Vital tooth.
- Patients having active pain in more than one tooth.
- Patients who had taken analgesics in 12 hours preceding the preparation.
- Any type of teeth with multi roots.
- Pulp hyperemia or any other conditions other than pulp necrosis like pulpitis or previously accessed teeth with temporary fillings and patients suffering from chronic disease (systemic diseases).
- Pregnant or mentally retarded patients.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Placebo Comparator
Calcium Hydroxide Mixed With Chlorhexidin
Calcium Hydroxide
Placebo
efficacy of calcium hydroxide and 2 % chlorhexidine gel and combination of both on the anaerobic bacteria, It was clear from the study that calcium hydroxide had limited efficacy against facultative anaerobes, but effective against obligate anaerobes while chlorhexidine only and combination group were effective against all species of anaerobic bacteria.
The antimicrobial activity of calcium hydroxide Ca(OH)2 is related to the release of hydroxyl ions in an aqueous environment leading to damage in the bacterial cytoplasmic membrane, protein denaturation and DNA damage
Mechanical preparation without intracanal medications.