TMS for Suicidal Crisis in Active Duty SMs (TMS4SI)
Suicide, Suicidal Ideation, Suicidal Impulses
About this trial
This is an interventional treatment trial for Suicide
Eligibility Criteria
Inclusion Criteria:
- All Active Duty SMs (regardless of sex, ethnicity, sexual or religious orientation) who are admitted to Eisenhower Army Medical Center (EAMC) Inpatient Psychiatric Service (IPS) with active suicidality or elevated risk for suicide regardless of most psychiatric diagnostic co-morbidity (see exclusion criteria). This includes in-patient admissions for suicidality and outpatient SMs with a Columbia-Suicide Severity Rating Scale (C-SSRS) score ≥3.
- Age 18 to 60
- Able to speak and read English.
Exclusion Criteria:
- Combative with staff.
- Comatose/catatonia.
- Incapacity owing to active mania or psychosis.
- Epilepsy, multiple sclerosis, or cerebrovascular accident.
- Non-removable metal in the head (Shrapnel; plates, aneurysm coils/clips; metal tattoos etc.)
- Implantable devices (pacemakers, stimulators, etc.)
- Schizophrenic or borderline personality.
- Positive screen for pregnancy.
- Already receiving TMS as a treatment for depression.
- Non-English reading and speaking subjects
Sites / Locations
- Eisenhower Army Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
TMS active
TMS sham
Neuronetics NeuroStar XPLOR magnetic stimulator - Active; Localization: Left prefrontal dorsolateral neocortex. Dose Delivery: Figure-8 solid core coil at 120% motor threshold, 10 Hz, 4 second train duration, 10 second interval for 30 minutes. Treatment Dose: ~4k/session, 12-15k/day, 36-45k total pulses. Sessions: 9 in total; 3/day for 3 consecutive days over and above SOC (Standard of Care).
Neuronetics NeuroStar XPLOR magnetic stimulator - Sham; Localization: Left prefrontal dorsolateral neocortex. Sham Delivery: Figure-8 solid core coil rendered inert via blocking insert. Dose: Zero pulses. Sessions: 9 in total; 3/day for 3 consecutive days over and above SOC.