search
Back to results

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE)

Primary Purpose

Endstage Renal Disease

Status
Recruiting
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Spironolactone 25Mg Tablet
Placebo Oral Tablet
Sponsored by
Population Health Research Institute
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Endstage Renal Disease

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  1. Age

    1. ≥45 years or
    2. ≥18 with a history of diabetes
  2. On dialysis ≥ 90 days

  3. On either

    1. Hemodialysis prescribed at least 2 treatments per week or
    2. Peritoneal dialysis prescribed with at least 1 exchange daily
  4. Provides informed consent

Exclusion Criteria:

  1. Hyperkalemia

    1. Serum potassium >5.8 mmol/L in the 6 weeks prior to enrollment or
    2. Serum potassium >6.0 mmol/L during active run-in
  2. Currently taking and unable to withdraw a mineralocorticoid receptor antagonist (i.e. spironolactone or eplerenone).
  3. Known sensitivity or allergy to spironolactone
  4. Current or planned pregnancy or breastfeeding
  5. Scheduled living related donor renal transplant
  6. Life expectancy < 6 months in the opinion of a treating nephrologist.
  7. Enrolled in another interventional trial testing a mineralocorticoid receptor antagonist or drug that has a known or likely interaction with spironolactone.
  8. Treating physician believes either spironolactone is either absolutely indicated or absolutely contra-indicated

Sites / Locations

  • Canberra HospitalRecruiting
  • Concord Repatriation General HospitalRecruiting
  • Northern Beaches HospitalRecruiting
  • Royal North Shore HospitalRecruiting
  • Sydney Adventist HospitalRecruiting
  • Sunshine Coast University HospitalRecruiting
  • Royal Brisbane Women's HospitalRecruiting
  • Princess Alexandra Hospital
  • Monash HealthRecruiting
  • Western Health - Sunshine HospitalRecruiting
  • Clinica Senhor do Bonfim
  • Clinica Senhor do Bonfim
  • Santa Casa de Misericordia de Belo Horizonte
  • Medical School of Botucatu of the Paulista State University - UNESPRecruiting
  • Fundacao Pro-RimRecruiting
  • Felicio Rocho Foundation - Hospital Felicio RochoRecruiting
  • Fundacao Hospitalar Sao Francisco de AssisRecruiting
  • Servico Ubaense de Nefrologia Ltda
  • Eurolatino Natal Pesquisas Medicas Ltda
  • Sociedade Hospitalar Angelina CaronRecruiting
  • Instituto Pro Renal BrazilRecruiting
  • Irmandade da Santa Casa de Misericordia de Porto Alegre -ISCMPARecruiting
  • Hospital de Clinicas de Porto AlegreRecruiting
  • Hospital Arquidiocesano Consul Carlos Reneaux
  • Sociedade Campineira de Educacao e Instrucao (SCEI)
  • Praxis Pesquisa Medica S/SRecruiting
  • Santa Casa de Misericordia de VotuporangaRecruiting
  • PROCARDIO Clinica CardiologicaRecruiting
  • Foothills HospitalRecruiting
  • University of AlbertaRecruiting
  • Dr.J. ConleyRecruiting
  • Dr. Marie MichaudRecruiting
  • St. Paul's HospitalRecruiting
  • Queen Elizabeth II Health Science CentreRecruiting
  • St. Joseph's HealthcareRecruiting
  • Queen's University at Kingston, Division of NephrologyRecruiting
  • Victoria HospitalRecruiting
  • Ottawa Hospital Research InstituteRecruiting
  • Health Sciences North Research InstituteRecruiting
  • St. Michael's HospitalRecruiting
  • Dr. Joanna SasalRecruiting
  • Dr. Annie-Claire Nadeau-FredetteRecruiting
  • Hopital du Sacre-Coeur de MontrealRecruiting
  • Centre Hospitalier de l'Universite de Montreal (CHUM)Recruiting
  • CHU de Quebec L'Hotel-Dieu de QuebecRecruiting
  • Nefrology
  • Clinefnorte CIA LtdaRecruiting
  • Nefromedi SARecruiting
  • Madras Medical College Chennai
  • CBCI Society for Medical Education
  • Narayana Hrudayalaya LimitedRecruiting
  • Fortis HospitalsRecruiting
  • K S Hegde Medical AcademyRecruiting
  • Nanjappa Hospitals ShimogaRecruiting
  • AsterMedCity
  • Caritas HospitalRecruiting
  • AIMS Hospital MumbaiRecruiting
  • National Health and Education Society
  • Ashirwad Hospital MumbaiRecruiting
  • Dhadiwal Hospital
  • ACE Hospital UneRecruiting
  • Aditya Birla HospitalRecruiting
  • Vijaya HospitalRecruiting
  • Apollo HospitalsRecruiting
  • Mahatma Gandhi Medical College and Reserach Institute
  • Nizam's Institute of Medical SciencesRecruiting
  • Yashoda Hospital
  • Osmania General HospitalRecruiting
  • Hospital Sultanah Aminah, Johor BahruRecruiting
  • Hospital Pakar Sultanah Fatimah
  • Universiti Kebangsaan Malaysia
  • Hospital Raja Permaisuri Bainun, IPOH
  • Hospital TaipingRecruiting
  • Hospital Pulau PinangRecruiting
  • Universiti Teknologi Mara (UiTM)
  • Hospital KajangRecruiting
  • Hospital Tengku Ampuan Rahimah KlangRecruiting
  • Hospital Kuala LumpurRecruiting
  • University Malaya Medical Centre (UMMC)Recruiting
  • Hospital Sultanah Nur Zahirah Kuala TerengganuRecruiting
  • Hospital Tengku Ampuan Afzan, KuantanRecruiting
  • Hospital Tuanku Jaafar, SerembanRecruiting
  • Hospital AmpangRecruiting
  • North Shore HospitalRecruiting
  • Waikato HospitalRecruiting
  • Auckland City Hospital
  • Dunedin HospitalRecruiting
  • Hawkes Bay HospitalRecruiting
  • Taranaki Base Hospital
  • Palmerston North HospitalRecruiting
  • Whangarei HospitalRecruiting
  • Philippines General HospitalRecruiting
  • Medical City General Hospital
  • National Kidney and Transplant InstituteRecruiting
  • Ulster HospitalRecruiting
  • Daisy Hill HospitalRecruiting
  • Kent & Canterbury HospitalRecruiting
  • Churchill HospitalRecruiting
  • Aberdeen Royal InfirmaryRecruiting
  • Belfast City HospitalRecruiting
  • Southmead HospitalRecruiting
  • University Hospital of Whales Health ParkRecruiting
  • Royal Derby HospitalRecruiting
  • Ninewells HospitalRecruiting
  • Queen Elizabeth University HospitalRecruiting
  • The Royal London HospitalRecruiting
  • Kings College HospitalRecruiting
  • City HospitalRecruiting
  • Salford Royal HospitalRecruiting
  • Canimel Center
  • Hospital de Clinicas "Dr. Manuel Quintela"
  • SEDIC CenterRecruiting
  • Cedina CenterRecruiting
  • Centro de Asistencia del Sindicato Medico del Uruguay-Institucion de Asistencia medica Privada (CASMU-IAMPP)Recruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Placebo Comparator

Active Comparator

Arm Label

Placebo Oral Tablet

Spironolactone 25 MG Tablet

Arm Description

A tablet with no active medication that will be an exact match of the active spironolactone in taste and appearance

25 mg of active spironolactone in tablet form

Outcomes

Primary Outcome Measures

CV Death or Hospitalization for Heart Failure

Secondary Outcome Measures

Cause specific death
Hospitalization for Heart Failure
All-cause death
All-cause Hospitalization
Hospitalization for hyperkalemia

Full Information

First Posted
January 11, 2017
Last Updated
February 22, 2023
Sponsor
Population Health Research Institute
Collaborators
Canadian Institutes of Health Research (CIHR)
search

1. Study Identification

Unique Protocol Identification Number
NCT03020303
Brief Title
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
Acronym
ACHIEVE
Official Title
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
Study Type
Interventional

2. Study Status

Record Verification Date
February 2023
Overall Recruitment Status
Recruiting
Study Start Date
July 7, 2017 (Actual)
Primary Completion Date
December 2024 (Anticipated)
Study Completion Date
January 2025 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Population Health Research Institute
Collaborators
Canadian Institutes of Health Research (CIHR)

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Product Manufactured in and Exported from the U.S.
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require dialysis. It works by blocking a hormone (aldosterone) in your body that causes high blood pressure and can damage the heart. Although spironolactone is very effective in patients that do not require dialysis, we do not know if spironolactone is effective in dialysis patients. Our research will help determine if spironolactone reduces heart failure and heart related deaths in dialysis patients. The purpose of this study is to determine if spironolactone reduces death or hospitalization for heart failure and is well tolerated in patients that require dialysis.
Detailed Description
Globally, over 2 million people receive dialysis for end-stage renal disease (ESRD) and 650,000 new patients start dialysis each year. Furthermore, the number of patients receiving dialysis is increasing as access to dialysis in the developing world improves and the prevalence of diabetes and vascular disease rises. Despite technical advances in dialysis, the outcomes for patients with ESRD are poor. Patients have frequent hospitalizations, poor health related quality of life and strikingly, high mortality rates. The most common cause of death in patients receiving dialysis is cardiovascular disease, accounting for >40% of all deaths. Observational studies suggest a causal pathway to cardiovascular death that includes progressive ventricular hypertrophy and dilatation as well as accelerated atherosclerosis. These changes result in myocardial ischemia and cardiac fibrosis that, in turn, lead to heart failure, arrhythmias and cardiac arrest. Strongly implicated in this pathophysiology is aldosterone. Mineralocorticoid receptor antagonists (MRAs) in non-ESRD patients, prevent cardiovascular deaths and small randomized controlled trials of MRAs in ESRD suggests they may reduce death and may be safe. Spironolactone is the most commonly used MRA worldwide. We will conduct a multicentre randomized controlled trial (RCT) to determine if spironolactone reduces cardiac mortality and hospitalizations for heart failure in patients treated with dialysis. This trial is called the Aldosterone bloCkade for Health Improvement EValuation in End-stage renal disease (ACHIEVE).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Endstage Renal Disease

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
2750 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Placebo Oral Tablet
Arm Type
Placebo Comparator
Arm Description
A tablet with no active medication that will be an exact match of the active spironolactone in taste and appearance
Arm Title
Spironolactone 25 MG Tablet
Arm Type
Active Comparator
Arm Description
25 mg of active spironolactone in tablet form
Intervention Type
Drug
Intervention Name(s)
Spironolactone 25Mg Tablet
Intervention Description
Randomized participants will receive a study supply of spironolactone 25 mg tablets. They will be instructed to take 1 tablet daily.
Intervention Type
Drug
Intervention Name(s)
Placebo Oral Tablet
Intervention Description
Randomized participants will receive a study supply of placebo tablets with no active medical ingredients. They will be instructed to take 1 tablet daily.
Primary Outcome Measure Information:
Title
CV Death or Hospitalization for Heart Failure
Time Frame
up to 5 years
Secondary Outcome Measure Information:
Title
Cause specific death
Time Frame
up to 5 years
Title
Hospitalization for Heart Failure
Time Frame
up to 5 years
Title
All-cause death
Time Frame
up to 5 years
Title
All-cause Hospitalization
Time Frame
up to 5 years
Title
Hospitalization for hyperkalemia
Time Frame
up to 5 years

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Age ≥45 years or ≥18 with a history of diabetes On dialysis ≥ 90 days On either Hemodialysis prescribed at least 2 treatments per week or Peritoneal dialysis prescribed with at least 1 exchange daily Provides informed consent Exclusion Criteria: Hyperkalemia Serum potassium >5.8 mmol/L in the 6 weeks prior to enrollment or Serum potassium >6.0 mmol/L during active run-in Currently taking and unable to withdraw a mineralocorticoid receptor antagonist (i.e. spironolactone or eplerenone). Known sensitivity or allergy to spironolactone Current or planned pregnancy or breastfeeding Scheduled living related donor renal transplant Life expectancy < 6 months in the opinion of a treating nephrologist. Enrolled in another interventional trial testing a mineralocorticoid receptor antagonist or drug that has a known or likely interaction with spironolactone. Treating physician believes either spironolactone is either absolutely indicated or absolutely contra-indicated
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Jessica Tyrwhitt, B.A.
Phone
9055274322
Ext
40555
Email
jessica.tyrwhitt@phri.ca
First Name & Middle Initial & Last Name or Official Title & Degree
Colin Hardy, B.A.
Phone
9055274322
Ext
40694
Email
colin.hardy@phri.ca
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Michael Walsh, MD, PhD
Organizational Affiliation
McMaster University
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
PJ Devereaux, MD, PhD
Organizational Affiliation
McMaster University
Official's Role
Study Chair
Facility Information:
Facility Name
Canberra Hospital
City
Garran
State/Province
Australian Capital Territory
ZIP/Postal Code
2605
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Girish S Talaulikar, MD
Phone
0262442955
Email
girish.talaulikar@act.gov.au
Facility Name
Concord Repatriation General Hospital
City
Concord
State/Province
New South Wales
ZIP/Postal Code
2139
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mona Razavian, MD
Phone
0402069898
Email
monarazavian@hotmail.com
Facility Name
Northern Beaches Hospital
City
Frenchs Forest
State/Province
New South Wales
ZIP/Postal Code
2086
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
John Paul Killen, MD
Email
john.killen@healthscope.com.au
Facility Name
Royal North Shore Hospital
City
Wahroonga
State/Province
New South Wales
ZIP/Postal Code
2076
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yvonne Shen, MD
Email
yvonne.Shen@health.nsw.gov.au
Facility Name
Sydney Adventist Hospital
City
Wahroonga
State/Province
New South Wales
ZIP/Postal Code
2076
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Muh Geot Wong, MD, PhD
Phone
0400854109
Email
muhgeot.wong@sydney.edu.au
Facility Name
Sunshine Coast University Hospital
City
Birtinya
State/Province
Queensland
ZIP/Postal Code
4575
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nicholas A Gray, MD
Phone
0752022882
Email
nicholas.gray@health.qld.gov.au
Facility Name
Royal Brisbane Women's Hospital
City
Herston
State/Province
Queensland
ZIP/Postal Code
4029
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Martin Wolley
Phone
610450954163
Email
martin.wolley@gmail.com
Facility Name
Princess Alexandra Hospital
City
Woolloongabba
State/Province
Queensland
ZIP/Postal Code
4102
Country
Australia
Individual Site Status
Completed
Facility Name
Monash Health
City
Clayton
State/Province
Victoria
ZIP/Postal Code
3168
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kevan Polkinghorne, MD
Email
kevan.polkinghorne@monash.edu
Facility Name
Western Health - Sunshine Hospital
City
Saint Albans
State/Province
Victoria
ZIP/Postal Code
3021
Country
Australia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Eugenia Pedagogos, MD
Email
eugenia.pedagogos@wh.org.au
Facility Name
Clinica Senhor do Bonfim
City
Feira De Santana
State/Province
Bahia
ZIP/Postal Code
44001-584
Country
Brazil
Individual Site Status
Withdrawn
Facility Name
Clinica Senhor do Bonfim
City
Salvador
State/Province
Bahia
ZIP/Postal Code
40415-065
Country
Brazil
Individual Site Status
Withdrawn
Facility Name
Santa Casa de Misericordia de Belo Horizonte
City
Santa Efigênia
State/Province
Belo Horizonte
ZIP/Postal Code
30150221
Country
Brazil
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gerson M Pereira Junior, MD
Phone
5531992134768
Email
gersonmpj@yahoo.com.br
Facility Name
Medical School of Botucatu of the Paulista State University - UNESP
City
Rubiao Junior
State/Province
Botucatu
ZIP/Postal Code
18618-687
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Luis Cuadrado Martin, MD
Phone
551438801171
Email
cuadrado@fmb.unesp.br
First Name & Middle Initial & Last Name & Degree
Luis Cuadrado Martin, MD
Facility Name
Fundacao Pro-Rim
City
Boa Vista
State/Province
Joinville
ZIP/Postal Code
89227680
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Viviane Calice-Silva, MD
Phone
5547991534003
Email
vivicalice@hotmail.com
Facility Name
Felicio Rocho Foundation - Hospital Felicio Rocho
City
Belo Horizonte
State/Province
Minas Gerais
ZIP/Postal Code
30110934
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marisa F Ferreira, MD
Phone
553135147195
Email
marisafferreira@gmail.com
Facility Name
Fundacao Hospitalar Sao Francisco de Assis
City
Belo Horizonte
State/Province
Minas Gerais
ZIP/Postal Code
31110580
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Geraldo M Medeiros de Paula, MD
Phone
5531983031600
Email
geraldo_paula@uol.com.br
Facility Name
Servico Ubaense de Nefrologia Ltda
City
Uba
State/Province
Minas Gerais
ZIP/Postal Code
36500008
Country
Brazil
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ricardo F Carvalho, MD
Phone
3235314046
Email
ricardofurtadodecarvalho@gmail.com
Facility Name
Eurolatino Natal Pesquisas Medicas Ltda
City
Petropolis
State/Province
Natal
ZIP/Postal Code
59020500
Country
Brazil
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Maria S Moura de Oliveira Paiva, MD
Phone
8499188732
Email
msanali@yahoo.com
Facility Name
Sociedade Hospitalar Angelina Caron
City
Campina Grande Do Sul
State/Province
Parana
ZIP/Postal Code
83430000
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Dalton B Precoma, MD
Phone
554136798783
Email
daltonprecoma@gmail.com
Facility Name
Instituto Pro Renal Brazil
City
Curitiba
State/Province
Parana
ZIP/Postal Code
80440-020
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Miguel Carlos Riella, MD
Email
mcriella@pro-renal.org.br
Facility Name
Irmandade da Santa Casa de Misericordia de Porto Alegre -ISCMPA
City
Bairro Santa Teresa
State/Province
Porto Alegre
ZIP/Postal Code
90020090
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joao C Goldani, MD
Phone
555132148640
Email
jcgoldani@gmail.com
Facility Name
Hospital de Clinicas de Porto Alegre
City
Porto Alegre
State/Province
Rio Grande Do Sul
ZIP/Postal Code
90035-903
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Fernando Thome, MD
Email
fthome@hcpa.edu.br
Facility Name
Hospital Arquidiocesano Consul Carlos Reneaux
City
Brusque
State/Province
Santa Catarina
ZIP/Postal Code
8835404
Country
Brazil
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Antonio de Padua Lanna, MD
Email
antoniopslanna@gmail.com
Facility Name
Sociedade Campineira de Educacao e Instrucao (SCEI)
City
Campinas
State/Province
Sao Paulo
ZIP/Postal Code
13034-685
Country
Brazil
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Aloisio Marchi da Rocha, MD
Email
am.rocha@uol.com.br
Facility Name
Praxis Pesquisa Medica S/S
City
Santo André
State/Province
Sao Paulo
ZIP/Postal Code
09090 790
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marcelo R Bacci, MD
Phone
551127598377
Email
mrbacci@yahoo.com
Facility Name
Santa Casa de Misericordia de Votuporanga
City
Votuporanga
State/Province
Sao Paulo
ZIP/Postal Code
15500003
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mauro E Hernandes, MD
Email
Maurohernandes0@gmail.com
Facility Name
PROCARDIO Clinica Cardiologica
City
Blumenau
State/Province
SC
ZIP/Postal Code
89010500
Country
Brazil
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sergio L Zimmermann, MD
Phone
554732223667
Email
slzimmermann@cardioblu.com.br
Facility Name
Foothills Hospital
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 2T9
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Braden Manns, MD
Phone
403-944-2595
Ext
4120
Email
braden.manns@albertahealthservices.ca
First Name & Middle Initial & Last Name & Degree
Braden Manns, MD
Facility Name
University of Alberta
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 2G3
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Neesh Pannu, MD
Phone
780-407-8520
Email
npannu@ualberta.ca
Facility Name
Dr.J. Conley
City
Kamloops
State/Province
British Colombia
ZIP/Postal Code
V2C 2T1
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joslyn Conley, MD
Phone
7782572509
Email
Joslyn.Conley@interiorhealth.ca
Facility Name
Dr. Marie Michaud
City
Kelowna
State/Province
British Colombia
ZIP/Postal Code
V1Y 1T2
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Marie Michaud, MD
Phone
7782572509
Email
marie.michaud@interiorhealth.ca
Facility Name
St. Paul's Hospital
City
Vancouver
State/Province
British Colombia
ZIP/Postal Code
V6Z 1Y6
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mercedeh Kiaii, MD
Phone
604-682-2344
Ext
62232
Email
mkiaii@providencehealth.bc.ca
First Name & Middle Initial & Last Name & Degree
Mercedeh Kiaii, MD
Facility Name
Queen Elizabeth II Health Science Centre
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H 1V7
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Karthik Tennankore, MD
Phone
9024732099
Email
karthikK.Tennankore@nshealth.ca
First Name & Middle Initial & Last Name & Degree
Steven D Soroka, MD
Phone
9024732099
Facility Name
St. Joseph's Healthcare
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8N 4A6
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christian Rabbat, MD
Phone
9055221155
Ext
33542
Email
rabbatc@mcmaster.ca
First Name & Middle Initial & Last Name & Degree
Scott Brimble, MD
Phone
9055221155
Ext
33787
Email
brimbles@gmail.com
Facility Name
Queen's University at Kingston, Division of Nephrology
City
Kingston
State/Province
Ontario
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Benjamin K Thomson, MD
Phone
613-533-6000
Ext
74500
Email
benjamin.thomson@kingstonhsc.ca
Facility Name
Victoria Hospital
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 5W9
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Matthew Weir, MD
Phone
519-685-8502
Email
matthew.weir@lhsc.on.ca
First Name & Middle Initial & Last Name & Degree
Matthew Weir, MD
Facility Name
Ottawa Hospital Research Institute
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1Y 4E9
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Debra Zimmerman, MD
Email
dzimmerman@toh.on.ca
First Name & Middle Initial & Last Name & Degree
Debra Zimmerman, MD
Facility Name
Health Sciences North Research Institute
City
Sudbury
State/Province
Ontario
ZIP/Postal Code
P3E 5J1
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
John P Harmon, MD
Phone
702-523-7300
Ext
2634
Email
jharmon@hsnsudbury.ca
First Name & Middle Initial & Last Name & Degree
Amy Nistico, MD
Phone
705-523-7300
Ext
3900
Email
anistico@hsnsudbury.ca
First Name & Middle Initial & Last Name & Degree
John P Harmon, MD
Facility Name
St. Michael's Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5B 1W8
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ron Wald, MD
Phone
416-864-3703
Email
waldr@smh.ca
First Name & Middle Initial & Last Name & Degree
Ron Wald, MD
Facility Name
Dr. Joanna Sasal
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M6R 1B5
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Joanna Sasal, MD
Phone
4165306772
Email
JSasal@stjoestoronto.ca
Facility Name
Dr. Annie-Claire Nadeau-Fredette
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H1T 2M4
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Annie-Claire Nadeau-Fredette, MD
Email
acnadeau-fredette.hmr@ssss.qouv.qc.ca
Facility Name
Hopital du Sacre-Coeur de Montreal
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H4J 1C5
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Francois Madore, MD
Phone
514-338-2222
Ext
2491
Email
f.madore@umontreal.ca
First Name & Middle Initial & Last Name & Degree
Francois Madore, MD
Facility Name
Centre Hospitalier de l'Universite de Montreal (CHUM)
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2W 1T8
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rita Suri, MD
Phone
514-890-800
Ext
36369
Email
rsuri.kidney@gmail.com
First Name & Middle Initial & Last Name & Degree
Rita Suri, MD
Facility Name
CHU de Quebec L'Hotel-Dieu de Quebec
City
Québec
ZIP/Postal Code
G1R 2J6
Country
Canada
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sacha DeSerres, MD
Phone
418-691-5464
Email
sacha.DeSerres@crchudequebec.ulaval.ca
First Name & Middle Initial & Last Name & Degree
Sacha DeSerres, MD
Facility Name
Nefrology
City
Quito
State/Province
Pichincha
ZIP/Postal Code
170131
Country
Ecuador
Individual Site Status
Withdrawn
Facility Name
Clinefnorte CIA Ltda
City
Quito
State/Province
Pichincha
ZIP/Postal Code
170303
Country
Ecuador
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Santiago Carrasco, MD
First Name & Middle Initial & Last Name & Degree
Doris Almeida, MD
Email
doryvon@hotmail.com
Facility Name
Nefromedi SA
City
Quito
State/Province
Pichincha
ZIP/Postal Code
170601
Country
Ecuador
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mayra Sanchez Velez, MD
Email
mayrisanzvelez@hotmail.com
Facility Name
Madras Medical College Chennai
City
Park Town
State/Province
Chennai
ZIP/Postal Code
600003
Country
India
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Natarajan Gopalakrishnan, MD
Phone
9444085404
Email
srigola751@yahoo.com
Facility Name
CBCI Society for Medical Education
City
Bangalore
State/Province
Karnataka
ZIP/Postal Code
560034
Country
India
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ravishankar Bonu, MD
Email
ravibonu@yahoo.co.in
Facility Name
Narayana Hrudayalaya Limited
City
Bangalore
State/Province
Karnataka
ZIP/Postal Code
560099
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ram M Bhatt, MD
Phone
919731285588
Email
docrambhat@yahoo.com
Facility Name
Fortis Hospitals
City
Bengaluru
State/Province
Karnataka
ZIP/Postal Code
560076
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rajanna Sreedhara, MD
Phone
9880150813
Email
rsreedhara@yahoo.com
Facility Name
K S Hegde Medical Academy
City
Mangaluru
State/Province
Karnataka
ZIP/Postal Code
575018
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pradeep Shenoy, MD
Email
mpradeepshenoy@gmail.com
Facility Name
Nanjappa Hospitals Shimoga
City
Shimoga
State/Province
Karnataka
ZIP/Postal Code
577201
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Y Anupama, MD
Email
anupamayj@gmail.com
Facility Name
AsterMedCity
City
Cochin
State/Province
Kerala
ZIP/Postal Code
682027
Country
India
Individual Site Status
Completed
Facility Name
Caritas Hospital
City
Kottayam
State/Province
Kerala
ZIP/Postal Code
686630
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Gopin Suresh, MD
Email
gopinathsuresh@rediffmail.com
Facility Name
AIMS Hospital Mumbai
City
Dombivli
State/Province
Maharashtra
ZIP/Postal Code
421203
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sachlin Gupta, MD
Email
ssg_sachin@yahoo.ca.in
Facility Name
National Health and Education Society
City
Mumbai
State/Province
Maharashtra
ZIP/Postal Code
400016
Country
India
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Alan F Almeida, MD
Phone
912224447612
Email
almeidaa@gmail.com
Facility Name
Ashirwad Hospital Mumbai
City
Mumbai
State/Province
Maharashtra
ZIP/Postal Code
421004
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hardik Shah, MD
Phone
09833919767
Email
drhardik74@hotmail.com
Facility Name
Dhadiwal Hospital
City
Nashik
State/Province
Maharashtra
ZIP/Postal Code
422002
Country
India
Individual Site Status
Terminated
Facility Name
ACE Hospital Une
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411004
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Atul Sajgure, MD
Phone
9890676278
Email
dratulsajgure@yahoo.com
Facility Name
Aditya Birla Hospital
City
Pune
State/Province
Maharashtra
ZIP/Postal Code
411033
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tarun Jeloka, MD
Phone
919670691221
Email
tjeloka@yahoo.com
Facility Name
Vijaya Hospital
City
Chennai
State/Province
Tamil Nadu
ZIP/Postal Code
600026
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Radha Venkatramanan, MD
Email
radhavenkatramanan@yahoo.com
Facility Name
Apollo Hospitals
City
Chennai
State/Province
Tamil Nadu
ZIP/Postal Code
600081
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Visweswar Reddy, MD
Phone
04425911111
Email
rishikeshsangeetha@yahoo.co.in
Facility Name
Mahatma Gandhi Medical College and Reserach Institute
City
Puducherry
State/Province
Tamil Nadu
ZIP/Postal Code
607402
Country
India
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hemachandar, MD
Email
nephrology@mgmcri.ac.in
Facility Name
Nizam's Institute of Medical Sciences
City
Hyderabad
State/Province
Telangana
ZIP/Postal Code
500082
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sree B Raju, MD
Phone
9848492951
Email
sreebhushan@hotmail.com
Facility Name
Yashoda Hospital
City
Susundra
State/Province
Telangana
ZIP/Postal Code
500003
Country
India
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Urmila Anandh, MD
Email
uanandh@gmail.com
Facility Name
Osmania General Hospital
City
Hyderabad
State/Province
Telegana
ZIP/Postal Code
500012
Country
India
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Manisha Sahay, MD
Email
drmanishasahay@gmail.com
Facility Name
Hospital Sultanah Aminah, Johor Bahru
City
Johor Bahru
State/Province
Johor
ZIP/Postal Code
80100
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wen J Liu, MD
Email
plnjl@yahoo.com
Facility Name
Hospital Pakar Sultanah Fatimah
City
Muar
State/Province
Johor
Country
Malaysia
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mah Doo Yee, MD
Email
mahdy426@yahoo.com.sg
Facility Name
Universiti Kebangsaan Malaysia
City
Cheras
State/Province
Kuala Lumpur
ZIP/Postal Code
56000
Country
Malaysia
Individual Site Status
Withdrawn
Facility Name
Hospital Raja Permaisuri Bainun, IPOH
City
Ipoh
State/Province
Perak
ZIP/Postal Code
30990
Country
Malaysia
Individual Site Status
Withdrawn
Facility Name
Hospital Taiping
City
Taiping
State/Province
Perak
ZIP/Postal Code
34000
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Teng K Seng, MD
Email
tgks79@gmail.com
Facility Name
Hospital Pulau Pinang
City
George Town
State/Province
Pulau Pinang
ZIP/Postal Code
10990
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
:oew Yew Fong, MD
Email
lyewfong@yahoo.com
Facility Name
Universiti Teknologi Mara (UiTM)
City
Batu Caves
State/Province
Selangor
Country
Malaysia
Individual Site Status
Withdrawn
Facility Name
Hospital Kajang
City
Kajang
State/Province
Selangor
ZIP/Postal Code
43000
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Sadanah A Mazlan, MD
Email
sadanahmazlan@gmail.com
Facility Name
Hospital Tengku Ampuan Rahimah Klang
City
Klang
State/Province
Selangor
ZIP/Postal Code
41200
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shahnaz Shah Firdaus Khan, MD
Email
shahsfkhan@yahoo.com.sg
Facility Name
Hospital Kuala Lumpur
City
Kuala Lumpur
ZIP/Postal Code
42896
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Wan Hazlina wan Mohamad, MD
Email
hazlina2080@yahoo.com
Facility Name
University Malaya Medical Centre (UMMC)
City
Kuala Lumpur
ZIP/Postal Code
59100
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Hafiz Adnan, MD
Email
wahafiz@ummc.edu.my
Facility Name
Hospital Sultanah Nur Zahirah Kuala Terengganu
City
Kuala Terengganu
ZIP/Postal Code
33158
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Zaiha Harun, MD
Email
zaiharun@gmail.com
Facility Name
Hospital Tengku Ampuan Afzan, Kuantan
City
Kuantan
ZIP/Postal Code
29142
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mohd Kamil Ahmad, MD
Email
mkaz_77@yahoo.com
Facility Name
Hospital Tuanku Jaafar, Seremban
City
Seremban
ZIP/Postal Code
25167
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Lily Mushahar, MD
Email
lilymushahar@gmail.com
Facility Name
Hospital Ampang
City
Setapak
ZIP/Postal Code
53200
Country
Malaysia
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Norazinizah Miswan, MD
Email
norazinizah@gmail.com
Facility Name
North Shore Hospital
City
Takapuna
State/Province
Auckland
ZIP/Postal Code
0620
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Janak de Zoysa, MD
Email
janak.dezoysa@waitematadhb.govt.nz
Facility Name
Waikato Hospital
City
Hamilton
State/Province
Waikato
ZIP/Postal Code
3204
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kannaiyan Rabindranath, MD
Email
k.rabindranath@waikatodhb.health.nz
Facility Name
Auckland City Hospital
City
Auckland
Country
New Zealand
Individual Site Status
Withdrawn
Facility Name
Dunedin Hospital
City
Dunedin
ZIP/Postal Code
9016
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Tracey Putt, MD
Email
tracey.putt@southerndhb.govt.nz
Facility Name
Hawkes Bay Hospital
City
Hastings
ZIP/Postal Code
4120
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Andrew McNally, MD
Email
andrew.mcnally@hawkesbaydhb.govt.nz
Facility Name
Taranaki Base Hospital
City
New Plymouth
ZIP/Postal Code
4310
Country
New Zealand
Individual Site Status
Withdrawn
Facility Name
Palmerston North Hospital
City
Palmerston North
ZIP/Postal Code
4442
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Norman Panlilio, MD
Email
norman.panlilio@midcentraldhb.govt.nz
Facility Name
Whangarei Hospital
City
Whangarei
ZIP/Postal Code
0148
Country
New Zealand
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Adam Mullan, MD
Email
adam.mullan@northlanddhb.org.nz
Facility Name
Philippines General Hospital
City
Ermita
State/Province
Manila
ZIP/Postal Code
1000
Country
Philippines
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rey Tan, MD
Phone
92850330987
Email
reyjaimetan@gmail.com
Facility Name
Medical City General Hospital
City
Pasig City
State/Province
Manila
ZIP/Postal Code
1605
Country
Philippines
Individual Site Status
Withdrawn
Facility Name
National Kidney and Transplant Institute
City
Quezon City
State/Province
Manila
ZIP/Postal Code
1101
Country
Philippines
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Anthony R Villanueva, MD
Phone
9178390041
Email
villanueva.russ@gmail.com
Facility Name
Ulster Hospital
City
Dundonald
State/Province
Belfast
ZIP/Postal Code
BT16 1RH
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Alastair Woodman
Email
alastair.woodman@setrust.hscni.net
Facility Name
Daisy Hill Hospital
City
Newry
State/Province
Down
ZIP/Postal Code
BT35 8DR
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Neal Morgan
Email
neal.morgan@southerntrust.hscni.net
Facility Name
Kent & Canterbury Hospital
City
Canterbury
State/Province
Kent
ZIP/Postal Code
CT1 3NG
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Timothy Doulton
Email
tdoulton@nhs.net
Facility Name
Churchill Hospital
City
Headington
State/Province
Oxford
ZIP/Postal Code
OX3 7LE
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Edward Sharples
Email
edward.sharples@ouh.nhs.uk
Facility Name
Aberdeen Royal Infirmary
City
Aberdeen
ZIP/Postal Code
AB23 2ZN
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Shona Methven
Email
shona.methven@nhs.scot
Facility Name
Belfast City Hospital
City
Belfast
ZIP/Postal Code
BT9 7AB
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Christopher Hill
Email
christopher.hill@belfasttrust.hscni.net
Facility Name
Southmead Hospital
City
Bristol
ZIP/Postal Code
BS10 5NB
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Albert Power
Email
albert.power@nbt.nhs.uk
Facility Name
University Hospital of Whales Health Park
City
Cardiff
ZIP/Postal Code
CF14 4XW
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rhodri Pyart
Email
rhodri.pyart@wales.nhs.uk
Facility Name
Royal Derby Hospital
City
Derby
ZIP/Postal Code
DE22 3NE
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Nick Selby
Email
nick.selby@nhs.net
Facility Name
Ninewells Hospital
City
Dundee
ZIP/Postal Code
DD1 9SY
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Samira Bell
Email
samira.bell@nhs.scot
Facility Name
Queen Elizabeth University Hospital
City
Glasgow
ZIP/Postal Code
G51 4TF
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Patrick Mark
Email
patrick.mark@glasgow.ac.uk
First Name & Middle Initial & Last Name & Degree
Rajan Patel
Email
rajan.patel@ggc.scot.nhs.uk
Facility Name
The Royal London Hospital
City
London
ZIP/Postal Code
E1 2ES
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kieran McCafferty
Email
kieran.mccafferty4@nhs.net
Facility Name
Kings College Hospital
City
London
ZIP/Postal Code
SE5 9RS
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Kate Bramham
Email
kate.bramham@kcl.ac.uk
Facility Name
City Hospital
City
Nottingham
ZIP/Postal Code
NG5 1PB
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Mark Jesky
Email
mark.jesky@nuh.nhs.uk
Facility Name
Salford Royal Hospital
City
Salford
ZIP/Postal Code
M6 8HD
Country
United Kingdom
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Rajkumar Chinnadurai
Email
rajkumar.chinnadurai@nca.nhs.uk
Facility Name
Canimel Center
City
Melo
State/Province
Cerro Largo
Country
Uruguay
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Pilar Varela, MD
Phone
598099690412
Email
varela_pilar@hotmail.com
Facility Name
Hospital de Clinicas "Dr. Manuel Quintela"
City
Montevideo
ZIP/Postal Code
11600
Country
Uruguay
Individual Site Status
Not yet recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Ricardo Silvarino, MD
Phone
59899619401
Email
rsilvarino@gmail.com
Facility Name
SEDIC Center
City
Montevideo
ZIP/Postal Code
11800
Country
Uruguay
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
David Miller, MD
Phone
24871581
Email
elvaca33@yahoo.com
Facility Name
Cedina Center
City
Montevideo
Country
Uruguay
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Juan C Diaz, MD
Phone
59894400364
Email
jcdiazsalvia@gmail.com
Facility Name
Centro de Asistencia del Sindicato Medico del Uruguay-Institucion de Asistencia medica Privada (CASMU-IAMPP)
City
Montevideo
Country
Uruguay
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Laura Sola, MD
Email
solalaura11@gmail.com

12. IPD Sharing Statement

Plan to Share IPD
No
IPD Sharing Plan Description
N/A - no plan to make IPD available to other researchers
Citations:
PubMed Identifier
27265777
Citation
Quach K, Lvtvyn L, Baigent C, Bueti J, Garg AX, Hawley C, Haynes R, Manns B, Perkovic V, Rabbat CG, Wald R, Walsh M. The Safety and Efficacy of Mineralocorticoid Receptor Antagonists in Patients Who Require Dialysis: A Systematic Review and Meta-analysis. Am J Kidney Dis. 2016 Oct;68(4):591-598. doi: 10.1053/j.ajkd.2016.04.011. Epub 2016 Jun 3.
Results Reference
background
PubMed Identifier
26138259
Citation
Walsh M, Manns B, Garg AX, Bueti J, Rabbat C, Smyth A, Tyrwhitt J, Bosch J, Gao P, Devereaux PJ, Wald R. The Safety of Eplerenone in Hemodialysis Patients: A Noninferiority Randomized Controlled Trial. Clin J Am Soc Nephrol. 2015 Sep 4;10(9):1602-8. doi: 10.2215/CJN.12371214. Epub 2015 Jul 2.
Results Reference
background
PubMed Identifier
34117077
Citation
Soomro QH, Charytan DM. Mineralocorticoid Receptor Antagonists and Cardiovascular Health with Kidney Failure. Clin J Am Soc Nephrol. 2021 Jun;16(6):843-845. doi: 10.2215/CJN.04460421. No abstract available.
Results Reference
derived
PubMed Identifier
34098039
Citation
Collister D, Mbuagbaw L, Guyatt G, Devereaux PJ, Tennankore KK, Reis G, Sola L, Xavier D, Jha V, Gallagher M, Dans AL, Liu W, de Zoysa J, Felix C, Mark PB, Li Z, Tyrwhitt J, Wilkinson J, Sheridan P, Yuan F, Walsh M; ACHIEVE investigators. Three week compared to seven week run-in period length and the assessment of pre-randomization adherence: A study within a trial. Contemp Clin Trials. 2021 Aug;107:106466. doi: 10.1016/j.cct.2021.106466. Epub 2021 Jun 5.
Results Reference
derived
PubMed Identifier
33586138
Citation
Hasegawa T, Nishiwaki H, Ota E, Levack WM, Noma H. Aldosterone antagonists for people with chronic kidney disease requiring dialysis. Cochrane Database Syst Rev. 2021 Feb 15;2(2):CD013109. doi: 10.1002/14651858.CD013109.pub2.
Results Reference
derived

Learn more about this trial

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

We'll reach out to this number within 24 hrs