Internal Limiting Membrane Peeling-reposition to Treat Idiopathic Macular Holes
Macular Hole, Surgery
About this trial
This is an interventional treatment trial for Macular Hole focused on measuring macular holes
Eligibility Criteria
Inclusion Criteria:
- The patients are diagnosed as macular hole by optical coherence tomography.
- Age ranges from 50 to 80 years.
- The patients have indication for surgery.
Exclusion Criteria:
- Traumatic macular hole.
- Combined with serious epiretinal membrane.
- Combined with diabetic retinopathy, hypertensive retinopathy.
- Combined with other ocular diseases, such as keratitis,uveitis,retinal vasculitis.
- - 6.0 diopters or more of spherical equivalent, 26mm or more of axial length.
- History of intraocular surgery.
- Presence of staphyloma.
- Other ocular diseases that could influence macular microstructure or visual function
Exit criteria:
- For reposition group, the patients will exit the research if the peeled ILM cannot reposition successfully.
- Due to adverse events, especially severe adverse events, the researchers consider withdrawal of patients based on concerns of safety and ethics;
- Drop out;
- The patients voluntarily withdraw the informed consent;
- Serious violation of the study protocol due to the subjects or investigators' reasons;
- Other reasons that the researchers believe for quitting the study.
Sites / Locations
- Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
peeling-reposition
peeling
After dying with Brilliant Blue G (Brilliant Blue; Gender, Germany) with the help of Constellation 23-gauge vitrectomy system (Alcon Laboratories Inc, Fort Worth, TX), the intervention of "peeling-reposition" was used to peel and unfold the ILM. And the postoperative posture would be prone position in two weeks for all patients after the operation.
After dying with Brilliant Blue G (Brilliant Blue; Gender, Germany) with the help of Constellation 23-gauge vitrectomy system, the intervention of "peeling" was used to grasped ILM with end-gripping forceps. And the postoperative posture would be prone position in two weeks for all patients after the operation.