Self-Face Recognition After Face Transplantation
Disfigurement of Face
About this trial
This is an interventional other trial for Disfigurement of Face focused on measuring Face Transplant
Eligibility Criteria
Inclusion Criteria:
- Patients who have suffered from severe facial disfigurement which warrant facial transplantation and have been evaluated and approved for transplantation, will be included.
Exclusion Criteria:
- Must be be able to enter and be scanned using MRI.
- Able to give full informed consent, before each scan and throughout their time in which they are participating in the study
- Able to perform the task to a high standard and also to have no underlying conditions that may alter how they process pictures of face
Participants must have none of the following, which cannot safely be removed without risk or discomfort while they enter the MRI unit:
- a pacemaker
- metal implants
- metal that cannot be removed on their body (e.g. shrapnel, piercings)
- metal clips
- an artificial heart valve
- a cochlear implant
- drug patches
- a contraceptive coil
- dental plates/braces with metal in
- hearing aids
Participants will also be excluded on the grounds of safety and comfort inside the MRI scanner if they have one of the following underlying conditions
- epilepsy
- diabetes
- heart disease
- thermoregulatory problems (problems regulating body temperature)
- a possibility of being pregnant
- currently breastfeeding
Participants will also be excluded on the grounds of MRI data quality for the following reasons:
- history of mental illness
- claustrophobia (discomfort in confined spaces)
- Neurological conditions
Sites / Locations
- New York University School of Medicine
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Pre-Transplant Time Point
Post-Transplant Time Point
Participants will be imaged in the Magnetic Resonance Imaging scanner (MRI)
Participants will be imaged in the Magnetic Resonance Imaging scanner (MRI). Patients for whom a pre-transplant fMRI was obtained will undergo functional MRI scanning at three-points post-transplant (approximately 2 and 4 months +/- 2 months post-operation and again at 1 year +/- 3 months post-transplant).