Aspirin in Asymmetrically Intrauterine Growth

Effect of Low-dose Aspirin on Fetal Weight of Idiopathic Asymmetrically Intrauterine Growth Restricted Fetuses With Abnormal Umbilical Doppler Indices

Intrauterine growth restriction refers to a fetus that has failed to get a specific measures by a gestational age. Asymmetric type of Intrauterine growth restriction is known by normal sized head with smaller abdomen.It is important to recognize the growth restricted fetuses, because these fetuses may have fetal or neonatal complications. When blood flow is increased, the oxygen and nutrients will deliver good to the fetus. The role of low-dose aspirin therapy in management of intrauterine growth restriction is controversial. It has been used, in many studies, in prevention of intrauterine growth restriction especially in women at high risk of pre-eclampsia or obstetrical antiphospholipid syndrome.

Inclusion Criteria: The pregnant women 28-30 weeks Idiopathic asymmetrically intrauterine growth restriction Middle aged women (20-35 years) Women with abnormal umbilical artery Doppler flow indices ( > +2 standard deviation above mean for gestational age) Exclusion Criteria: Women less than 20 and more than 35 years hypertensive or diabetic women any type of smoking multiple pregnancies amniotic fluid index <5 cm premature pre-labor rupture of membranes abnormal placenta any fetal congenital malformations. women had absent diastolic flow or reversed flow in umbilical artery at the time of recruitment.