ECPR for Refractory Out-Of-Hospital Cardiac Arrest (EROCA)
Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest
About this trial
This is an interventional treatment trial for Cardiac Arrest focused on measuring Out-of-hospital cardiac arrest, Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Resuscitation, Extracorporeal Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation, CPR, ECPR, ECMO, Emergency Medical Services, EMS, OHCA
Eligibility Criteria
Inclusion Criteria:
- OHCA of presumed non-traumatic etiology requiring CPR
- Predicted arrival time at ECPR-capable hospital within timeframe specified
- Witnessed arrest or initial shockable rhythm (VT or VF)
- Persistent cardiac arrest after initial cardiac rhythm analysis and shock (if shock is indicated)
Exclusion Criteria:
- Sustained return of spontaneous circulation (ROSC)
- Advanced directive indicating do not attempt resuscitation (DNAR) or do not intubate (DNI)
- Preexisting evidence of opting out of study
- Prisoner
- Pregnant (obvious or known)
- ECPR capable ED is not at the destination hospital as determined by EMS
- Legally authorized representative (LAR) or family member aware of study and refuses study participation at the scene
Sites / Locations
- University of Michigan Hospital
Arms of the Study
Arm 1
Arm 2
No Intervention
Experimental
Standard Care
Expedited Transport
Basic Life Support (BLS) and Advanced Cardiovascular Life Support (ACLS) by Emergency Medical Services (EMS) per existing EMS protocols at the scene of the cardiac arrest.
Intervention: Expedited Transport with Mechanical CPR. After initial Basic Life Support (BLS) and Advanced Cardiovascular Life Support (ACLS) by Emergency Medical Services (EMS) per existing EMS protocols, patients with refractory cardiac arrest are transported to an ECPR capable emergency department with ongoing mechanical CPR and ACLS for possible initiation of extracorporeal cardiopulmonary resuscitation (ECPR).