The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients
Retinitis Pigmentosa, Retinal Degeneration, Cannabis
About this trial
This is an interventional basic science trial for Retinitis Pigmentosa focused on measuring retinitis pigmentosa, retinal degeneration, cannabis, THC, CBD, electrophysiology, visual functions, eye, retina
Eligibility Criteria
Inclusion Criteria:
- consenting adults
- generally healthy with or without retinitis pigmentosa
Exclusion Criteria:
- chronic or acute disease other than retinitis pigmentosa
- use of medication
- congestive heart failure
- recent use of illicit drugs (past month)
- history of drug dependency
- history of psychiatric disorder in subject or immediate relatives
- pregnancy
Sites / Locations
- Hadassah Medical CenterRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
healthy
Retinitis Pigmentosa
All subjects will undergo a full ocular exam and visual functions will be assessed before and after the administration of a single dose of cannabis (THC:CBD 1:40). On the second study day all subjects will receive a single dose of cannabis (THC:CBD 1:1) and undergo the full ocular exam again.
All subjects will undergo a full ocular exam and visual functions will be assessed before and after the administration of a single dose of cannabis (THC:CBD 1:40). On the second study day all subjects will receive a single dose of cannabis (THC:CBD 1:1) and undergo the full ocular exam again.