Effects of Physical Exercise to Prevent Osteoporosis in Postmenopausal Women (Osteo_women)
Primary Purpose
Osteoporosis, Postmenopausal, Osteoporosis, Osteopenia, Physical Activity
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
walking at an intense pace
osteoporosis specific-oriented training
Sponsored by
About this trial
This is an interventional treatment trial for Osteoporosis, Postmenopausal
Eligibility Criteria
Inclusion Criteria:
- Postmenopausal woman
- Pharmacological treatment (VitaminD+Calcium)
Exclusion Criteria:
- Disease or physical-mental condition which prevents to perform the proposed physical exercise
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Experimental
Arm Label
Control
Experimental
Arm Description
walking at an intense pace
osteoporosis specific-oriented training
Outcomes
Primary Outcome Measures
Femoral neck T-score
The score compares femoral neck bone mineral density to a reference mean
Lumbar spine T-score
The score compares lumbar spine bone mineral density to a reference mean
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT03091088
Brief Title
Effects of Physical Exercise to Prevent Osteoporosis in Postmenopausal Women
Acronym
Osteo_women
Official Title
Efecto de Dos Tipos de Ejercicio físico Para Prevenir la Osteoporosis en Mujeres Postmenopausicas, un Ensayo Clinico Aleatorizado
Study Type
Interventional
2. Study Status
Record Verification Date
March 2017
Overall Recruitment Status
Completed
Study Start Date
February 1, 2011 (Actual)
Primary Completion Date
July 1, 2013 (Actual)
Study Completion Date
December 30, 2016 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Valencia
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
According to the World Health Organization criteria, osteoporosis was defined as a bone mineral density that lies 2.5 standard deviations or more below the average value for young healthy women. Osteoporosis is a major cause of fractures and can lead to serious complications in postmenopausal women. For this reason, approaches to prevent the appearance and progression of osteoporosis are of primary importance. This randomized clinical trial analyzes the effects of two types of physical exercise oriented to prevent osteoporosis in postmenopausal women with pharmacological supplements of Calcium and Vitamin-D.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Osteoporosis, Postmenopausal, Osteoporosis, Osteopenia, Physical Activity
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderOutcomes Assessor
Allocation
Randomized
Enrollment
36 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Control
Arm Type
Active Comparator
Arm Description
walking at an intense pace
Arm Title
Experimental
Arm Type
Experimental
Arm Description
osteoporosis specific-oriented training
Intervention Type
Other
Intervention Name(s)
walking at an intense pace
Intervention Description
Participants walk 6 kilometers in 1 hour at least 3 times per week
Intervention Type
Other
Intervention Name(s)
osteoporosis specific-oriented training
Intervention Description
1 hour of physical activity, 2 times per week, based on the Asociación Española con la Osteoporosis y la Artrosis (AECOS) recommendations. Sessions are divided in 15 minutes of warmup (8 to 10, 60-second exercises), 30-35 minutes of combined exercises with loads and weights, as well as high intensity exercises, and 10-15 minutes of cooldown activities (based on Frederick relaxation techniques)
Primary Outcome Measure Information:
Title
Femoral neck T-score
Description
The score compares femoral neck bone mineral density to a reference mean
Time Frame
Change from baseline score at two years
Title
Lumbar spine T-score
Description
The score compares lumbar spine bone mineral density to a reference mean
Time Frame
Change from baseline score at two years
10. Eligibility
Sex
Female
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Postmenopausal woman
Pharmacological treatment (VitaminD+Calcium)
Exclusion Criteria:
Disease or physical-mental condition which prevents to perform the proposed physical exercise
12. IPD Sharing Statement
Plan to Share IPD
Undecided
Citations:
PubMed Identifier
29040219
Citation
Garcia-Gomariz C, Blasco JM, Macian-Romero C, Guillem-Hernandez E, Igual-Camacho C. Effect of 2 years of endurance and high-impact training on preventing osteoporosis in postmenopausal women: randomized clinical trial. Menopause. 2018 Mar;25(3):301-306. doi: 10.1097/GME.0000000000001005.
Results Reference
derived
Learn more about this trial
Effects of Physical Exercise to Prevent Osteoporosis in Postmenopausal Women
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