Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis
Primary Progressive Multiple Sclerosis, Hemiparesis
About this trial
This is an interventional treatment trial for Primary Progressive Multiple Sclerosis focused on measuring Constraint-induced movement therapy, video game, virtual reality, upper extremity, CI therapy, rehabilitation, hemiparesis, MS, multiple sclerosis, progressive multiple sclerosis, primary progressive multiple sclerosis, secondary progressive multiple sclerosis, motor, physical therapy, physiotherapy, occupational therapy, arm, hand
Eligibility Criteria
Inclusion Criteria:
- Patients who have progressive multiple sclerosis resulting in upper extremity motor impairment.
- Have the ability to comprehend and participate in basic elements of the therapy.
- Have substantial non-use in the more affected upper extremity.
Exclusion Criteria:
- Are currently participating in other experimental trials.
- Are currently participating in additional upper extremity therapy.
- Experienced relapse within the past 6 months.
- Too frail to undergo intensive rehabilitation,
- Those with serious, uncontrolled medical problems.
Sites / Locations
- The Ohio State University, 2154 Dodd Hall
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Immediate Treatment
Delayed Treatment
Patients will receive an in-home consultation with an occupational/physical therapist in which they are educated about the intervention, the system is set up, and they are guided through use of the system. After initial contact, therapist support will be available via telephone to address specific difficulties with operating the system, as well as three additional home visits throughout the 3 week intervention. The rehabilitation program requires use of the rehabilitation gaming system for 1.5 hours daily for 21 consecutive days (equivalent dosage to standard CI therapy), limb activation device worn for 90% of waking hours, and completion of the automated transfer package to facilitate real-world arm use (e.g., problem-solving modules, daily monitoring of arm use). After completing the intervention, the patient will receive additional consultation with the therapist to formulate goals for follow-up. Follow-up assessments will be conducted to assess long-term retention of motor gains.
Patients will receive an in-home consultation with an occupational/physical therapist in which they are educated about the intervention, the system is set up, and they are guided through use of the system. After initial contact, therapist support will be available via telephone to address specific difficulties with operating the system, as well as three additional home visits throughout the 3 week intervention. The rehabilitation program requires use of the rehabilitation gaming system for 1.5 hours daily for 21 consecutive days (equivalent dosage to standard CI therapy), limb activation device worn for 90% of waking hours, and completion of the automated transfer package to facilitate real-world arm use (e.g., problem-solving modules, daily monitoring of arm use). After completing the intervention, the patient will receive additional consultation with the therapist to formulate goals for follow-up. Follow-up assessments will be conducted to assess long-term retention of motor gains.