Mood and Influenza Vaccine Response: A Feasibility Trial
Vaccination; Infection
About this trial
This is an interventional basic science trial for Vaccination; Infection focused on measuring Positive Affect, Positive Mood, Influenza Vaccination, Vaccination, Randomised Controlled Trial
Eligibility Criteria
Inclusion Criteria:
- Males and Females aged 65-85 years (inclusive)
- Received influenza vaccination for the 2016/17 season
- Eligible to receive 2017/18 influenza vaccination as part of usual care
- Ability to give informed consent
Exclusion Criteria:
- Males and Females aged less than 65 or over 85 years (exclusive)
- Did not receive influenza vaccination for the 2016/17 season
- Ineligible to receive 2017/18 influenza vaccination as part of usual care
- Unable to provide informed consent
Deemed by health care provider to be:
- Too physically frail to participate
- Diagnosed with dementia or other cognitive condition which would make participation difficult
- Insufficient command of English language
- Influenza vaccination contraindicated
- Sufficiently impaired of hearing or vision that exposure to the intervention or control video content as intended would be compromised
- Those for whom the collection of blood samples is contraindicated.
Sites / Locations
- University of Nottingham
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Experimental
Active Control
Participants in the experimental condition will view a video designed to induce positive affect. This includes 3 short comedy clips (fork handles sketch, the two Ronnie's; A room with a view - faulty towers; Tim Vine Live stand-up extract), uplifting music (Jailhouse Rock - Elvis Presley; Happy Together - The Turtles), jokes and positive imagery. The content of the intervention has been informed by patient and public involvement, focus groups with older adults, and pilot testing.
Participants in the control condition will view a video of matched length to the experimental condition video, but not designed to induce mood change. This includes short documentary clips (a pride in pencils; model railways, lecture extract on hydration), neutral music and images.