Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia
Total Knee Replacement Surgery
About this trial
This is an interventional supportive care trial for Total Knee Replacement Surgery
Eligibility Criteria
Inclusion Criteria:
- all patient who will undergo total knee arthroplasty
Exclusion Criteria:
- patients who will not agree to participate in the study
- patients who will die during the research timeframe
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Spinal block
General anesthesia
Intrathecal 10 mg Heavy Marcaine, 200 mcg Morphine + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg ideal body weight diluted with 100cc Normal Saline + Total Knee Replacement ( which will not be the intervention of interest)
1-3 mg IV propofol 0.5 mg/kg IV Rocuronium + Fentanyl 2-3 mcg/kg + Morphine 0.1mg/kg IV Maintenance: Volatile anesthetic + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg ideal body weight diluted with 100cc Normal Saline + Total Knee Replacement ( which will not be the intervention of interest)