Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis
Muscle Cramp, Cirrhosis
About this trial
This is an interventional supportive care trial for Muscle Cramp
Eligibility Criteria
Inclusion Criteria:
- Patients at least 18 years of age in the Vanderbilt Medical Center Hepatology Practice
- diagnosis of cirrhosis
- Self report regular muscle cramping
Exclusion Criteria:
- Patients without cirrhosis
- Patients under the age of 18
- Pregnant women
Sites / Locations
- Vanderbilt University Medical Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Vitamin E then Ropinirole
Ropinirole then Vitamin E
Patients will be provided with vitamin E, 400 international units (IU), at baseline. Patient demographics will be collected along with baseline lab data including magnesium, potassium, albumin, and total bilirubin levels. After 3 months, patients will be switched to Ropinirole. Surveys measuring muscle cramp frequency and intensity will be collected at baseline, 3 months, and 6 months.
Patients will be prescribed ropinirole at baseline. Patient demographics will be collected along with baseline lab data including magnesium, potassium, albumin, and total bilirubin levels. After 3 months, patients will be switched to vitamin E, 400 international units (IU). Surveys measuring muscle cramp frequency and intensity will be collected at baseline, 3 months, and 6 months.