Study of Testosterone and Athlete Response (STAR)
Athletic Performance, Testosterone, Women's Health: Female Athlete/Female Athlete Triad
About this trial
This is an interventional basic science trial for Athletic Performance focused on measuring female athletes, testosterone, physical performance, body composition
Eligibility Criteria
Inclusion criteria are: healthy menstruating women; 18-35 yrs of age; BMI 19-25; non-smoking; having a moderate to high self-reported level of recreational physical activity (minimum of three hours of endurance and/or strength training per week); not taking hormonal contraception; and willing to use highly efficient non-hormonal contraception during the study such as:
- Intrauterine device
- Bilateral tubal occlusion
- Vasectomised partner
- Same-sex partner
- Sexual abstinence
Exclusion criteria are: the presence of cardiovascular, liver, biliary or renal disease; hyperlipidemia; uncontrolled high blood pressure; endocrinological disorder; oligomenorrhea (menstrual intervals of more than 6 weeks) or amenorrhea (no menstruation for at least 3 months); pregnancy; a history of thromboembolic disorder; any malignancy; and intake of hormonal contraception the last two months prior to the study.
Sites / Locations
- Department of Obstetrics and Gynecology, Karolinska University Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Group A
Group B
Testosterone cream 1% (Andro-Feme® )
Placebo cream