Systematic Light Exposure for Fatigue in Breast Cancer Patients
Cancer-related Problem/Condition, Fatigue, Circadian Rhythm Disorders
About this trial
This is an interventional supportive care trial for Cancer-related Problem/Condition focused on measuring Breast Cancer, Oncology, Circadian Rhythm, Light Therapy, Chemotherapy side effects
Eligibility Criteria
Inclusion Criteria:
- Newly diagnosed patients with stage 1 through 3a Breast Cancer scheduled to receive a 12-week, 16-week, 18-week, 20-week, or 24-week chemotherapy regimen, adjuvant, neoadjuvant, or already receiving chemotherapy.
- MSH, COH and MSK can recruit participants schedule to go on aromatase inhibitors after treatment.
- Currently over the age of 18.
- English language proficient.
- Able to provide informed consent.
Exclusion Criteria:
- Under age 18
- Breast cancer patients scheduled to undergo chemo regimen other than the 12-week, 18-week, 20-week, or 24-week regimen
- Stage 3B breast cancer inflammatory or Stage 4 breast cancer
- Pregnancy
- Currently employed in night shift work
- Confounding underlying medical illnesses which may cause fatigue (e.g., severe Anemia not controlled by medication, per self-report corroborated by medical chart review (e.g., Hb<10gm/dl))
- Eye Diseases which limit the ability of light to be processed (e.g., untreated cataracts, severe glaucoma, macular degeneration, blindness, pupil dilation problems or retina damage)
- Secondary cancer diagnosis (prior or current) within the past 5 years
- Severe sleep disorders (e.g., Narcolepsy)
- Self- reported history of bipolar disorder or manic episodes (which is a contra-indication for light treatment)
- Severe psychological impairment (e.g., hospitalization for depressive episode in the past 12 months
- Previous use of light therapy to alleviate fatigue or depressive symptoms
- Lives outside of the United States throughout the duration of study
Sites / Locations
- City of Hope Cancer Center
- Icahn School of Medicine at Mount Sinai
- Memorial Sloan-Kettering Cancer Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Experimental
Active Comparator
Adjuvant, Experimental Light
Adjuvant, Comparison Light
Neo-Adjuvant, Experimental Light
Neo-Adjuvant, Comparison Light
30 minutes of experimental systematic light exposure daily for duration of chemotherapy treatment.
30 minutes of comparison systematic light exposure daily for duration of chemotherapy treatment.
30 minutes of experimental systematic light exposure daily for duration of chemotherapy treatment.
30 minutes of comparison systematic light exposure daily for duration of chemotherapy treatment.