Robotic Therapy and Brain Stimulation in the Early Phase After Stroke
Stroke
About this trial
This is an interventional other trial for Stroke focused on measuring stroke, robotic therapy, transcranial direct current stimulation
Eligibility Criteria
Inclusion Criteria:
Ischemic or hemorrhagic stroke onset from 3 days to 9 weeks before, confirmed by computed tomography or magnetic resonance imaging.
Motor impairment of an upper limb, defined as a score between 1 - 3 in the Medical Research Council Scale, for at lest one the following movements: elbow extension, shoulder flexion, or shoulder extension.
Ability to provide written informed consent.
Ability to comply with the schedule of interventions and evaluations in the protocol.
Exclusion Criteria:
Severe spasticity at the paretic elbow, wrist or fingers, defined as a score of > 3 in the Modified Ashworth Spasticity Scale.
No active shoulder and elbow movements
Uncontrolled medical problems such as end-stage cancer or renal disease
Pregnancy
Potential contraindications to transcranial direct current stimulation: history of seizures, lesions on the scalp, intracranial metal implants, prior intracranial surgery, use of drugs that interfere on cortical excitability (such as antiepileptic drugs, benzodiazepines)
Other neurological disorders such as Parkinson's disease
Psychiatric illness
Aphasia or severe cognitive deficits that compromise comprehension of the experimental protocol or ability to provide consent.
Hemineglect
Cerebellar lesions or on cerebellar pathways
Contact precautions
Sites / Locations
- Suzana Bleckmann Reis
Arms of the Study
Arm 1
Arm 2
Active Comparator
Sham Comparator
Active stimulation + robotic therapy
Sham stimulation + robotic therapy
Active transcranial direct current stimulation will be applied during 20 minutes prior to robotic training. Number of interventions sessions: 1
Sham transcranial direct current stimulation will be applied during 20 minutes prior to robotic training. Number of interventions sessions: 1