Tranexamic Acid in Cyanotic Heart Defects
Postoperative Hemorrhage
About this trial
This is an interventional prevention trial for Postoperative Hemorrhage focused on measuring Pediatric, Cyanotic heart disease, Tranexamic acid, Postoperative blood loss
Eligibility Criteria
Inclusion Criteria:
2 to 12 years cyanotic cardiac disease with cardio pulmonary bypass
Exclusion Criteria:
Previous cardiac surgery any operation within 48 hr., previous inotropes or mechanical vention aprotinin exposure Liver or renal impairment Coagulation or hemostatic dysfunction within the last 7 days before surgery.
Sites / Locations
- Faculty of Medicine
Arms of the Study
Arm 1
Arm 2
Arm 3
Placebo Comparator
Active Comparator
Active Comparator
Group 1
Group 2
Group 3
In control group will receive normal saline,
Intravenous Tranexamic acid group will received Intravenous 50 mg / kg followed by infusion of 1 mg/kg/hr for six hours
the topical Tranexamic acid group will receive 50 mg / kg poured before sternal closure.