High-intensity Interval Training on Cardiorespiratory Fitness in Overweight Women
Primary Purpose
Healthy Volunteers
Status
Completed
Phase
Not Applicable
Locations
Colombia
Study Type
Interventional
Intervention
High-intensity interval training
Comparator: Moderate-intensity continuous exercise
Sponsored by

About this trial
This is an interventional treatment trial for Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
- Overweight (≥ 25 kg/m-2) women 18 to 44 years.
- Healthy volunteers.
- Perform ≤ 600 Met/min/week.
Exclusion Criteria:
- Perform high-intensity interval exercise in the last six month.
- Smoker.
- History of asthma.
- History of diabetes.
- History of hypertension.
- History of cardiovascular disease.
- History of coronary heart disease.
- Arrhythmias.
- Personal history of surgical procedures in the last three months
- Uncontrolled non-communicable diseases
- Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids.
- Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
- Psychoactive drug abuse.
Sites / Locations
- Universidad de Antioquia
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
High-intensity interval training
Moderate-intensity continuous exercise
Arm Description
Outcomes
Primary Outcome Measures
Change in maximal oxygen consumption
Maximal oxygen consumption will be obtained using a graded exercise test on a treadmill (Trackmaster® model TMX 425C) using a portable K4b2 gas analyzer (Cosmed Inc., IL, USA)
Secondary Outcome Measures
Change in total body fat
Total body fat will be obtained using an Omron® HBF-510 (Omron Healthcare, Inc. Bannockburn, IL, USA) bioelectrical impedance machine.
Full Information
NCT ID
NCT03300895
First Posted
September 28, 2017
Last Updated
February 1, 2019
Sponsor
Universidad de Antioquia
1. Study Identification
Unique Protocol Identification Number
NCT03300895
Brief Title
High-intensity Interval Training on Cardiorespiratory Fitness in Overweight Women
Official Title
Effect of Low-volume High-intensity Interval Training on Cardiorespiratory Fitness and Total Body Fat in Overweight Women
Study Type
Interventional
2. Study Status
Record Verification Date
February 2019
Overall Recruitment Status
Completed
Study Start Date
August 14, 2017 (Actual)
Primary Completion Date
November 30, 2018 (Actual)
Study Completion Date
November 30, 2018 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Universidad de Antioquia
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No
5. Study Description
Brief Summary
High-intensity interval training (HIIT) is currently considered one of the most effective strategies to improved cardiorespiratory fitness, which is recognized as a protective factor for cardiovascular diseases and metabolic diseases such as overweight and obesity. However, current evidence is still limited and requires clarity (frequency, time per session and intensity) regarding to greater increases attributed to HIIT.
The aim of this study is to compare the effect of a low-volume high-intensity interval training versus a moderate-intensity continuous exercise on maximal oxygen consumption in overweight women 18 to 44 years old.
Detailed Description
Thirty-six women will be randomly assigned to one of two aerobic exercise on a real-life setting supervised for a physical activity instructor. The interventions will performed three times a week for ten-weeks (on alternate days).
The first two weeks will correspond to the conditioning period (30 minutes between 55-65% of maximum heart rate (HRmax). From week three, 18 participants will perform 30 minutes of continuous exercise at an intensity between 65-75 % of HRmax, and the remaining 18 will complete 21.5 minutes of interval exercise at an intensity between 90-95% of HRmax, with recoveries between 50-55% of HRmax.
All Participants will be evaluated to measure their maximal oxygen consumption, total body fat, waist circumference, body mass index, systolic blood pressure, diastolic blood pressure, prior to start the interventions and at the end of the program (week 11).
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Healthy Volunteers
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
35 (Actual)
8. Arms, Groups, and Interventions
Arm Title
High-intensity interval training
Arm Type
Experimental
Arm Title
Moderate-intensity continuous exercise
Arm Type
Active Comparator
Intervention Type
Other
Intervention Name(s)
High-intensity interval training
Intervention Description
21.5 minutes of high-intensity interval exercise at an intensity between 90-95 of HRmax (15x30 s), with recoveries at 50-60% of HRmax (14x60 s). 24 sessions, 3x weekly of walking and running outdoors on a sports field in a supervised manner.
Intervention Type
Other
Intervention Name(s)
Comparator: Moderate-intensity continuous exercise
Intervention Description
30 minutes of continuous exercise at an intensity between 65-75% of HRmax. 24 sessions, 3x weekly of walking and jogging outdoors on a sports field in a supervised manner
Primary Outcome Measure Information:
Title
Change in maximal oxygen consumption
Description
Maximal oxygen consumption will be obtained using a graded exercise test on a treadmill (Trackmaster® model TMX 425C) using a portable K4b2 gas analyzer (Cosmed Inc., IL, USA)
Time Frame
Baseline and after 10 weeks
Secondary Outcome Measure Information:
Title
Change in total body fat
Description
Total body fat will be obtained using an Omron® HBF-510 (Omron Healthcare, Inc. Bannockburn, IL, USA) bioelectrical impedance machine.
Time Frame
Baseline and after 10 weeks
10. Eligibility
Sex
Female
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
44 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Overweight (≥ 25 kg/m-2) women 18 to 44 years.
Healthy volunteers.
Perform ≤ 600 Met/min/week.
Exclusion Criteria:
Perform high-intensity interval exercise in the last six month.
Smoker.
History of asthma.
History of diabetes.
History of hypertension.
History of cardiovascular disease.
History of coronary heart disease.
Arrhythmias.
Personal history of surgical procedures in the last three months
Uncontrolled non-communicable diseases
Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids.
Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
Psychoactive drug abuse.
Facility Information:
Facility Name
Universidad de Antioquia
City
Medellín
State/Province
Antioquia
Country
Colombia
12. IPD Sharing Statement
Plan to Share IPD
No
Citations:
PubMed Identifier
35228846
Citation
Arboleda-Serna VH, Patino-Villada FA, Pinzon-Castro DA, Arango-Velez EF. Effects of low-volume, high-intensity interval training on maximal oxygen consumption, body fat percentage and health-related quality of life in women with overweight: A randomized controlled trial. J Exerc Sci Fit. 2022 Apr;20(2):108-112. doi: 10.1016/j.jesf.2022.01.004. Epub 2022 Feb 4.
Results Reference
derived
Learn more about this trial
High-intensity Interval Training on Cardiorespiratory Fitness in Overweight Women
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