The Alcohol-Pain Connection: Mechanisms and Genetic/Psychological Correlates
Pain, Alcohol Drinking, Acute Pain
About this trial
This is an interventional basic science trial for Pain focused on measuring Alcohol, Pain
Eligibility Criteria
Inclusion Criteria:
- be 21-64 years of age
- be classified as a moderate or heavy drinker based on the Quantity-Frequency-Variability Questionnaire, which will assure that participants currently (last 3 months) consume alcohol in amounts similar to what will be administered or available in the proposed experiments
Exclusion Criteria:
- current acute or chronic pain
- chili pepper allergies (contraindicated for capsaicin)
- current use of prescription pain medications
- any possibility of being pregnant (verified at session via a pregnancy test)
- self-reported history of or treatment for psychiatric or alcohol/other drug problems
- participants who are under the age of 21 or who do not have a government issued ID; and
- medical conditions that contraindicate the use of alcohol (e.g., diabetes, liver disease).
Sites / Locations
- Syracuse University
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Experimental
Experimental
Experimental
Experimental
Placebo Comparator
Experimental
Placebo Comparator
Experimental
Low Alcohol Consumption and No Pain Induction
Low Alcohol Consumption and Pain Induction
Moderate Alcohol Consumption and No Pain Induction
Moderate Alcohol Consumption and Pain Induction
Placebo Alcohol Consumption and No Pain Induction
Placebo Alcohol Consumption and Pain Induction
Control and No Pain Induction
Control and Pain Induction
Condition 1: Low alcohol consumption Condition 2: No pain group
Condition 1: Low alcohol consumption Condition 2: Pain group
Condition 1: Moderate alcohol consumption Condition 2: No pain group
Condition 1: Moderate alcohol consumption Condition 2: Pain group
Condition 1: Placebo alcohol consumption Condition 2: No pain group
Condition 1: Placebo alcohol consumption Condition 2: Pain group
Condition 1: No alcohol consumption Condition 2: No pain group
Condition 1: No alcohol consumption Condition 2: Pain group