Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory
Glioma, Brain Tumor, Primary
About this trial
This is an interventional supportive care trial for Glioma focused on measuring High grade gliomas (WHO grade III or IV), Low grade gliomas (WHO Grade II)
Eligibility Criteria
Inclusion Criteria:
- Confirmed primary brain tumor diagnosis via MRI and their neuro-oncologist
- A minimum of 2 months post-surgical resection or biopsy(if applicable)
- and/or a minimum 1 month post radiation treatment (if applicable)
- Karnofsky performance status more than 60
- Estimated intelligence at least 80 (standard score)
- Demonstrated attention difficulties (T-score of at least 65 on attention questionnaire or 1 or more standard deviations below mean on direct attention measures)
- No history of cognitive disorder
- No history of mood disorder
- Predicted life expectancy of at least 12 months
- Computer capability at home or provided a departmental iPad Mini to borrow for study purposes
- Primarily English speaking
- Aged 18+ (for which there is available age-adjusted neuropsychological testing standardization / normative data)
Exclusion Criteria:
- If they are not patients of Massey Cancer Center or do not meet the inclusion criteria listed above
Sites / Locations
- Virginia Commonwealth University/Massey Cancer Center
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
High grade gliomas(WHO grade III or IV; n=15)
Low grade gliomas(WHO grade II; n=15)
The two groups will follow identical study timelines. Participants will receive a 1 hour training session on CogMed® (PI or trained graduate student). Participants will complete 5 weeks of CogMed® training within their own home. It consists of 25 training sessions. Each session lasts 30-45 minutes.The study team will check in with participants once a week via phone or email. Brief neuropsychological evaluations will be conducted at 4 time points. Each assessment will take approximately 30-60 minutes. Each participant will receive a $25 gift card to the VCU medical center gift shop at two time points.
The two groups will follow identical study timelines. Participants will receive a 1 hour training session on CogMed® (PI or trained graduate student). Participants will complete 5 weeks of CogMed® training within their own home. It consists of 25 training sessions. Each session lasts 30-45 minutes.The study team will check in with participants once a week via phone or email. Brief neuropsychological evaluations will be conducted at 4 time points. Each assessment will take approximately 30-60 minutes. Each participant will receive a $25 gift card to the VCU medical center gift shop at two time points.