Comparing the Efficacy of Two Methods for the Therapy of Uterine Adhesion
Intrauterine Adhesion
About this trial
This is an interventional prevention trial for Intrauterine Adhesion focused on measuring Asherman syndrome, uterine stent, hysteroscopy
Eligibility Criteria
Inclusion Criteria:
- age 20-45 years.
- previously diagnostic hysteroscopy confirmed adhesion score ≧5, according to the American Fertility Society (AFS).
- complains of menstruation disorder and reproductive dysfunction.
- informed consent.
Exclusion Criteria:
- premature menopause,
- presence of other intrauterine lesions (e.g. polyps, myoma, septa), and
- presence of severe intercurrent illness (e.g. systemic disease, coagulative disorders, severe kidney and liver diseases),
- adhesions limited to the lower uterine cavity or the cervical canal.
Sites / Locations
- Beijing Obstetrics and Gynecology Hospital, Capital Medical UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
dried biological amnion graft
disposable balloon uterine stent only
dried biological amnion graft patients, who are with IUA, treated by uterine application of dried biological amnion graft + disposable balloon uterine stent + hormones (estradiol valerate tablets+dydrogesterone Tablets) following hysteroscopic adhesiolysis.
disposable balloon uterine stent patients, who are with IUA, treated by uterine application of disposable balloon uterine stent only + hormones (estradiol valerate tablets+dydrogesterone Tablets) following hysteroscopic adhesiolysis.