Lexical Priming by Music in Alzheimer's Disease and Healthy Aging (PriMus)
Alzheimer Disease
About this trial
This is an interventional other trial for Alzheimer Disease focused on measuring Lexical priming, Healthy Aging
Eligibility Criteria
Inclusion Criteria for patients :
- Presence of diagnostic criteria for Alzheimer's disease
- Age ≥ 65 years
- MMSE (Mini-mental state Examination) ≥ 20
Exclusion Criteria for patient :
- Unstable clinical presentation or language presentation in the foreground
- Cognitive disorder of etiology different from that of Alzheimer's disease
Inclusion Criteria for volunteers :
- Age ≥ 18 years
- Absence of neurological or psychiatric antecedents
- For those aged 65 or over: MMSE (Mini-mental state Examination) greater than or equal to 27; non-pathological performance against the 5 words of Dubois and the verbal fluency test.
Exclusion Criteria for volunteers :
- Visual or auditory disorders insufficiently corrected
- Oral or written expression in French insufficient to carry out tests
- Consumption of psychotropic drugs not stabilized
Sites / Locations
- CHU de Saint Etienne
Arms of the Study
Arm 1
Arm 2
Other
Other
patient with Alzheimer's Disease
healthy volunteer
Exposure to familiar songs : a) Words and Music (sing condition), b) Words only (spoken condition) and c) Music only (instrumental condition) After each song : rate the popularity of the song on a scale of 1 to 5. Music Experience Questionnaire : questions about the past music training Implicit tasks memory : a) Completion of trigrams : freely complete the first 3 letters of a word. b) lexical decision : judge whether an audibly presented sound sequence is a word existing in the French language or not.
Exposure to familiar songs : a) Words and Music (sing condition), b) Words only (spoken condition) and c) Music only (instrumental condition) After each song : rate the popularity of the song on a scale of 1 to 5. Music Experience Questionnaire : questions about the past music training Implicit tasks memory : a) Completion of trigrams : freely complete the first 3 letters of a word. b) lexical decision : judge whether an audibly presented sound sequence is a word existing in the French language or not. For volunteer over 65 years : Mini Mental State Examination, 5 words by Dubois and fluence verbal test