Iron Status in Infants in Ethiopia.
Iron-deficiency, Iron Deficiency Anemia, Aluminium Intoxication
About this trial
This is an interventional prevention trial for Iron-deficiency
Eligibility Criteria
Inclusion Criteria:
- 18-36 months of age (at screening)
- The child is able to eat at least two injera meals per day
- The informed consent form has been read and signed by the caregiver (or has been read out to the caregiver in case of illiteracy)
Exclusion Criteria:
- Severely deficient in Hb (<70g/L)
- Severe underweight (weight for age Z score < -3),
- Severe wasting (weight for height Z score < -3)
- Chronic or acute illness or other conditions that in the opinion of the Principle Investigator (PI) or co-researchers would jeopardize the safety or rights of a participant in the trial or would render the participant unable to comply with the protocol
- Participants taking part in other studies requiring the drawing of blood
- Not planning long-term residence in study site
Sites / Locations
- Center for Food Science and Nutrition, Addis Ababa University
- Swiss Federal Institute of Technology ETH Zurich
Arms of the Study
Arm 1
Arm 2
Arm 3
Placebo Comparator
Experimental
Active Comparator
Traditionally Threshed Teff (TTT)
Lab Threshed Teff (LTT)
Fortified Lab Threshed Teff (FTT)
The control group will consume injera based on teff threshed under the hooves of cattle. We plan to have a certain number of teff flour suppliers, where the teff is traditionally threshed and contains at least 50 mg Fe per 100 g flour.
The intervention group will consume injera based on teff flour that has been lab threshed using a modern teff threshing machine.
This arm will be the positive control group consuming Ferrous Sulphate drops ( with injera that consist of lab-threshed teff. The Fe drops have to be consumed with the meal and will provide an additional 6 mg of Ferrous sulfate to the diet of the children.