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Emotion Recognition Training in Antisocial Violent Offenders With Psychopathic Traits

Primary Purpose

Psychopathy, Violent Aggressive Behavior, Emotional Problem

Status
Unknown status
Phase
Not Applicable
Locations
Germany
Study Type
Interventional
Intervention
SEE Training
GAZE Training
Sponsored by
University Hospital Tuebingen
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Psychopathy

Eligibility Criteria

18 Years - 65 Years (Adult, Older Adult)MaleDoes not accept healthy volunteers

Inclusion Criteria:

  • Confirmed ASPD diagnosis
  • PCL-Score available
  • arrested for committing violent crimes

Exclusion Criteria:

  • Insufficient knowledge of the German language
  • Diagnosed with schizophrenia
  • Substance abuse
  • Neurological disease (e.g. epilepsy)
  • Mental retardation

Sites / Locations

  • University of TübingenRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

SEE Training

GAZE Training

Arm Description

The training sequence comprises four weekly sessions using a modified dote-probe paradigm (fearful vs. neutral expression).

The GAZE training sequence comprises four weekly sessions using a modified dote-probe paradigm (averted vs. directed gaze).

Outcomes

Primary Outcome Measures

Animated morph task
Morphed images are presented, beginning with the neutral face that progresses into one of the six affective expressions. This procedure creates the impression of an animated clip depicting the development of facial emotive expressions. Participants are instructed to press a button as soon as they are able to identify the emerging expression.

Secondary Outcome Measures

Unconscious processing of affective facial expressions during interocular suppression in a breaking Continuous flash suppression paradigm
Change in processing of unaware/unconsciously perceived emotional stimuli as assessed by number of faces correctly identified
Eye-Tracking
Change in recognition and visual processing of emotional faces as indicated by raw scores and group means for dwell time, total dwell time, and time to first AOI (mouth/eye region) hit
Ambivalence Task
Change in interpretation of ambiguous emotional faces as indicated by number of hostile judgments
Emotional search paradigm
Assessment of implicit perceptual biases for and explicit categorization of facial expression in an emotional search paradigm (change pre- to post-intervention)
Affective prosody
Change in recognition of non-verbal emotional aspects of language as assessed by number of correct classifications
Multifaceted empathy test
Assessment of cognitive and emotional empathy (change pre- to post-intervention)

Full Information

First Posted
December 12, 2017
Last Updated
December 18, 2017
Sponsor
University Hospital Tuebingen
Collaborators
German Research Foundation
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1. Study Identification

Unique Protocol Identification Number
NCT03382808
Brief Title
Emotion Recognition Training in Antisocial Violent Offenders With Psychopathic Traits
Official Title
Emotion Recognition Training in Antisocial Violent Offenders With Psychopathic Traits
Study Type
Interventional

2. Study Status

Record Verification Date
December 2017
Overall Recruitment Status
Unknown status
Study Start Date
April 1, 2017 (Actual)
Primary Completion Date
March 1, 2019 (Anticipated)
Study Completion Date
December 31, 2019 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University Hospital Tuebingen
Collaborators
German Research Foundation

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
No

5. Study Description

Brief Summary
Impaired recognition of affective facial expressions has been conclusively linked to antisocial and psychopathy. However, little is known about the modifiability of this deficit. This study aims to investigate whether and under which circumstances the proposed perceptual insensitivity can be addressed with a brief implicit training approach.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Psychopathy, Violent Aggressive Behavior, Emotional Problem

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantOutcomes Assessor
Allocation
Randomized
Enrollment
80 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
SEE Training
Arm Type
Experimental
Arm Description
The training sequence comprises four weekly sessions using a modified dote-probe paradigm (fearful vs. neutral expression).
Arm Title
GAZE Training
Arm Type
Active Comparator
Arm Description
The GAZE training sequence comprises four weekly sessions using a modified dote-probe paradigm (averted vs. directed gaze).
Intervention Type
Behavioral
Intervention Name(s)
SEE Training
Intervention Description
Participants are first presented with a fixation cross which indicates the beginning of a trial and is immediately followed by a bilateral presentation of a neutral and a fearful image (face) of the same model identity. The fearful expression is always replaced by an arrow pointing to the left or the right which remaines active until the participant indicates via button-press which direction the arrow is pointing to. The model identity, the position of the fearful cue and the arrow probe direction are pseudo-randomized across trials with no more than three identical sequential occurrences on each parameter. Each session consists of 360 trials in total, with 120 distinct trial types and three repetitions. Participants are trained with neutral and 75% fearful expressions only in the first session; the intensity of the fearful cue is successively decreased by 15% at every subsequent session.
Intervention Type
Behavioral
Intervention Name(s)
GAZE Training
Intervention Description
Participants are first presented with a fixation cross, which indicates the beginning of a trial and is immediately followed by a bilateral presentation of a direct gaze-image (neutral face) and an image of a neutral face (same model identity) displaying deviated gaze. The averted gaze-face is always replaced by an arrow pointing to the left or the right which remaines active until the participant indicates via button-press which direction the arrow is pointing to. The model identity, the position of the fearful cue and the arrow probe direction are pseudo-randomized across trials with no more than three identical sequential occurrences on each parameter. Each session consists of 360 trials in total, with 120 distinct trial types and three repetitions. Participants are trained with direct and 100% averted gaze images only in the first session; the intensity of the deviated gaze cue is successively decreased by 20% at every subsequent session.
Primary Outcome Measure Information:
Title
Animated morph task
Description
Morphed images are presented, beginning with the neutral face that progresses into one of the six affective expressions. This procedure creates the impression of an animated clip depicting the development of facial emotive expressions. Participants are instructed to press a button as soon as they are able to identify the emerging expression.
Time Frame
change from pre-treatment to post-treatment after 8 weeks
Secondary Outcome Measure Information:
Title
Unconscious processing of affective facial expressions during interocular suppression in a breaking Continuous flash suppression paradigm
Description
Change in processing of unaware/unconsciously perceived emotional stimuli as assessed by number of faces correctly identified
Time Frame
pre-treatment, after 8 weeks (post-treatment)
Title
Eye-Tracking
Description
Change in recognition and visual processing of emotional faces as indicated by raw scores and group means for dwell time, total dwell time, and time to first AOI (mouth/eye region) hit
Time Frame
pre-treatment, after 8 weeks (post-treatment)
Title
Ambivalence Task
Description
Change in interpretation of ambiguous emotional faces as indicated by number of hostile judgments
Time Frame
pre-treatment, after 8 weeks (post-treatment)
Title
Emotional search paradigm
Description
Assessment of implicit perceptual biases for and explicit categorization of facial expression in an emotional search paradigm (change pre- to post-intervention)
Time Frame
pre-treatment, after 8 weeks (post-treatment)
Title
Affective prosody
Description
Change in recognition of non-verbal emotional aspects of language as assessed by number of correct classifications
Time Frame
pre-treatment, after 8 weeks (post-treatment)
Title
Multifaceted empathy test
Description
Assessment of cognitive and emotional empathy (change pre- to post-intervention)
Time Frame
pre-treatment, after 8 weeks (post-treatment)

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Confirmed ASPD diagnosis PCL-Score available arrested for committing violent crimes Exclusion Criteria: Insufficient knowledge of the German language Diagnosed with schizophrenia Substance abuse Neurological disease (e.g. epilepsy) Mental retardation
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Michael Schönenberg, PhD
Phone
004970712978355
Email
michael.schoenenberg@uni-tuebingen.de
First Name & Middle Initial & Last Name or Official Title & Degree
Martin Hautzinger, Prof.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Michael Schönenberg, PhD
Organizational Affiliation
University Hospital Tuebingen
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Tübingen
City
Tübingen
State/Province
Baden Würrtemberg
ZIP/Postal Code
72074
Country
Germany
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Michael Schönenberg, PhD
Phone
004970712978355
Email
michael.schoenenberg@uni-tuebingen.de

12. IPD Sharing Statement

Plan to Share IPD
No
Citations:
PubMed Identifier
23809680
Citation
Schonenberg M, Christian S, Gausser AK, Mayer SV, Hautzinger M, Jusyte A. Addressing perceptual insensitivity to facial affect in violent offenders: first evidence for the efficacy of a novel implicit training approach. Psychol Med. 2014 Apr;44(5):1043-52. doi: 10.1017/S0033291713001517. Epub 2013 Jul 1.
Results Reference
background
PubMed Identifier
32880104
Citation
Gibbon S, Khalifa NR, Cheung NH, Vollm BA, McCarthy L. Psychological interventions for antisocial personality disorder. Cochrane Database Syst Rev. 2020 Sep 3;9(9):CD007668. doi: 10.1002/14651858.CD007668.pub3.
Results Reference
derived

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Emotion Recognition Training in Antisocial Violent Offenders With Psychopathic Traits

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