Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
Pain, Referred
About this trial
This is an interventional supportive care trial for Pain, Referred
Eligibility Criteria
Inclusion criteria:
- elective cesarean delivery
- planned spinal anesthesia
Exclusion criteria:
- Non-English speaking
- Urgent or emergent cesarean delivery
- Active labor [defined as: >4cm cervical dilation or regular contractions noted on tocometer (>2 contractions in a 10 minute period for 30 consecutive minutes)]
- Chronic antepartum opioid use
- History of substance abuse (alcohol or drug)
- Current tobacco use
- Chronic steroid use
Sites / Locations
- Albert Einstein College of Medicine/ Montefiore Medical Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
bupivacaine 0.25%
bupivacaine 0.25% + epinephrine
Saline Solution
standard intrathecal bupivacaine (Marcaine) 0.75% 1.5-1.7 ml, intrathecal morphine (Duramorph) 150mcg plus intrathecal fentanyl 10 mcg + 20 ml subcutaneous bupivacaine (Marcaine) 0.25%
standard intrathecal bupivacaine (Marcaine) 0.75% 1.5-1.7 ml, intrathecal morphine (Duramorph) 150mcg plus intrathecal fentanyl 10 mcg + 20 ml subcutaneous bupivacaine (Marcaine) 0.25% with Epinephrine
standard intrathecal bupivacaine (Marcaine) 0.75% 1.5-1.7 ml, intrathecal morphine (Duramorph) 150mcg plus intrathecal fentanyl 10 mcg + 20 ml subcutaneous NACL 0.9% (placebo)