Personalizing Sleep Interventions to Prevent Type 2 Diabetes in Community Dwelling Adults With Pre-Diabetes
PreDiabetes
About this trial
This is an interventional prevention trial for PreDiabetes focused on measuring sleep, sleep extension, sleep patterns, type 2 diabetes, glucose regulation, behavioral intervention, adults
Eligibility Criteria
Inclusion Criteria:
- Glycated hemoglobin (Hemoglobin A1C) greater than or equal to 5.7% and less than 6.5%.
- Restricted sleep defined as less than 6.5 hours average work day sleep (actigraphy confirmed).
- employed greater than or equal to 20 hours of work per week (self report).
Exclusion Criteria:
- type 2 diabetes (Hemoglobin A1C greater than or equal to 6.5%)
- pregnancy or lactation (self-report)
- hemophilia (self-report)
- obstructive sleep apnea (Multivariable Apnea Prediction Index > 0.50 or Home sleep apnea test Apnea-Hypopnea Index >10 events/hour).
- insomnia (Insomnia Severity Index greater than 10)
- moderate/severe or severe depression (PROMIS-D-short form raw score greater than or equal to 27 or T-score greater than or equal to 64.7)
- alcohol abuse/dependence (Alcohol Use Disorders Identification Test greater than or equal to 10).
- sleep promoting medications (self-report)
hypoglycemic agents (except metformin) (self-report)
--current chemotherapy treatments (self-report)
- extended napping (greater than or equal to 2 naps per day or greater than 90 minutes naps per day on 3 or more days of the week) (actigraphy-confirmed).
- Shift work during the past 2 months or planned during intervention period (self-report).
- Trans-meridian travel in the past 4 weeks or planned during intervention period (self-report).
- No difference between work day and free day sleep duration (actigraphy confirmed).
Sites / Locations
- NYU LangoneRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Sleep extension
Habitual sleep
Participants in the sleep extension group will keep daily sleep diaries. Sleep diaries will be reviewed with the participant and an instructor trained in Cognitive Behavioral Therapy for Insomnia (CBTI) on a weekly basis. These weekly sessions will take place by telephone or videoconferencing.
Participants in the habitual sleep group will be instructed to keep their habitual bedtimes and wake times. Participants will keep daily sleep diaries that will we reviewed by a study team member each week. These weekly sessions will take place by telephone or videoconferencing.