Intravenous Iron for Iron-deficiency Anemia in Pregnancy: a Randomized Controlled Trial (IVIDA)
Iron Deficiency Anemia of Pregnancy, Iron Malabsorption
About this trial
This is an interventional treatment trial for Iron Deficiency Anemia of Pregnancy focused on measuring Iron Deficiency Anemia of Pregnancy, oral iron supplementation, parenteral iron supplementation, maternal anemia
Eligibility Criteria
Inclusion Criteria:
- Iron-deficiency anemia (serum ferritin <30 micrograms, normal hemoglobin electrophoresis, and hemoglobin <10 mg/dL), planned delivery at Barnes-Jewish Hospital
Exclusion Criteria:
- Non-iron-deficiency anemia, multiple gestation, prenatally diagnosed major fetal anomalies, known aneuploidy, planned delivery at other hospital, inability to obtain consent
Sites / Locations
- Indiana University School of Medicine
- Center for Outpatient Health, Washington University in St. Louis
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Intravenous iron dextran infusion
Oral ferrous sulfate supplementation
Women randomized to receive intravenous iron infusion will receive a single infusion of dextran 1000mg IV as an inpatient on the antepartum or Labor & Delivery Unit. They will receive continuous fetal monitoring for 30 minutes before and after the infusion as well for the duration of the infusion
Women randomized to continue oral iron will continue to take ferrous sulfate 325mg one to three tablets daily, with the final dose at the discretion of the patient's obstetric provider.