Comparison of the Onset Times and Durations of Actions of Different Local Anesthetic Mixture Solutions [CODLAM] (CODLAM)
Injury Arm
About this trial
This is an interventional basic science trial for Injury Arm focused on measuring brachial plexus block, local anesthetic mixture solution, axillary-supraclavicular approach, outcome quality, lidocaine, bupivacaine, onset time, duration action local anesthetic, postoperative analgesia
Eligibility Criteria
Inclusion Criteria:
- elective or emergency trauma surgery of hand or forearm
- consented to ultrasound-guided BPB
Exclusion Criteria:
- continuous peripheral nerve catheter technique or bilateral block was planned
- the patient refused to participate
- psycho-mental conditions interfering with consent or assessment
- pre-existing chronic pain condition or daily analgesic or sedative consumption
- sedative or analgesic premedication
- pre-existing neurological disorders affecting the brachial plexus
- obstructive sleep apnea
- contraindications to PNB including local skin infections or allergy to LA agents.
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Active Comparator
LB Group
BS Group
LS Group
BL Group
Ultrasound-guided brachial plexus block for LB Group (15 ml lidocaine 1% + 15 ml bupivacaine 0.5%)
Ultrasound-guided brachial plexus block for BS Group (20 ml bupivacaine 0.5% + 10 ml normal saline)
Ultrasound-guided brachial plexus block for LS Group (20 ml lidocaine 1% + 10 ml normal saline)
and Ultrasound-guided brachial plexus block for BL Group (20 ml bupivacaine 0.5% + 10 ml lidocaine 1%)