Dexmedetomidine in Serratus Plane Block for Mastectomy
Postoperative Pain
About this trial
This is an interventional supportive care trial for Postoperative Pain
Eligibility Criteria
Inclusion Criteria:
- Patients of American Society of Anesthesiologists (ASA) grade I - III.
- Scheduled for unilateral modified radical mastectomy.
Exclusion Criteria:
- Patient with the skin infection in the axilla.
- Allergy to local anesthetics of the amide type.
- Patient refusal.
Sites / Locations
- Oncology Center Mansoura University.
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Placebo Comparator
Bupivacaine-Dexmedetomidine group
Bupivacaine group
Saline group
After general anesthesia, patients will receive a cocktail of isobaric bupivacaine 2.5 mg/ml plus 5 micrograms (mcg)/ml adrenaline and 1mcg/kg dexmedetomidine in a volume of 0.5 ml/kg injected superficial to serratus muscle between and below latissimus dorsi muscle.
After general anesthesia, patients will receive a cocktail of isobaric bupivacaine 2.5 mg/ml plus 5 micrograms (mcg)/ml adrenaline in a volume of 0.5 ml/kg injected superficial to serratus muscle between and below latissimus dorsi muscle.
This group will serve as a control and blinding group and will receive saline infiltration in the same manner.