PRINT Trial (Platelet Rich Injection vs Needle Tenotomy) (PRINT)
Lateral Epicondylitis, Tendinosis, Elbow, Tennis
About this trial
This is an interventional treatment trial for Lateral Epicondylitis
Eligibility Criteria
Inclusion Criteria:
- Adults: 18 years and older
- Diagnosed with: Lateral epicondylitis or common extensor tendinopathy
- Has had symptoms for more than 3 months
- Failed conservative treatment with an eccentric loading protocol that was formally taught and attempted for at least 6 weeks.
- Failed at least 1 corticosteroid injection (anatomically or ultrasound guided injection)
Exclusion Criteria:
- Age less than 18 years
- Pregnant or breast feeding females
- Previous surgery to the area of interest
- Previous needling procedure to the area of interest in the last 3 months
- Previous steroid injection to the area of interest in the last 3 months
- Previous PRP or autologous blood or prolotherapy to the area of interest
- Patients treated for a Workers Compensation related injury
- Any systemic disease that may play a causative role or delay in healing such as rheumatoid arthritis, lupus, immunodeficiency
- Severe degenerative bone disease or severe vascular disease that may be a confounder
Diagnosis of concomitant nerve involvement in area of interest:
- Carpal tunnel, radial nerve impingement, cervical radiculopathy in patients with lateral epicondylitis
- Any contraindication to use of lidocaine or injections
- Will record if patient is taking any medications that may alter bleeding or clotting such as aspirin, Plavix, Coumadin, Aggrenox, heparin, lovenox, etc, but this will be a relative contraindication and decision is made by patient and provider after informed consent.
Sites / Locations
- KP-LAMC
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Needle Tenotomy
Platelet Rich Plasma
1 group will be assigned to get the standard treatment for chronic tendinopathy, percutaneous needle tenotomy (PNT). It is currently considered a standard treatment option. Ultrasound guided PNT with approximately 25 passes through the tendon and enthesis with approximately an 18 gauge needle with adequate amount of anesthetic (lidocaine) for effective anesthesia. Investigators will keep track of the number of passes through the tendon. Investigators will keep track of the amount and type of anesthetic used
1 group will be assigned to the PRP arm. Investigators will have a trained provider draw the blood, and prepare the PRP according to manufacturer and departmental (KP) protocol. Ultrasound guided injection of this PRP using approximately an 18 gauge needle with a single pass through the tendon into affected area as demonstrated on ultrasound. Adequate amount of anesthetic will be given in a separate syringe with adequate amount of anesthetic (lidocaine) for effective anesthesia. Investigators will keep track of amount and type of anesthetic used. The amount of anesthesia will be the same in both arms of the study