MBSR in Rheumatoid Arthritis Patients With Controlled Disease But Persistent Depressive Symptoms (PARIS-D)
Rheumatoid Arthritis, Depressive Symptoms
About this trial
This is an interventional supportive care trial for Rheumatoid Arthritis
Eligibility Criteria
Inclusion Criteria:
- ≥18 years, with stable (3 months) disease modifying antirheumatic drugs (DMARDs) and/or biologic-treated RA (meeting classification criteria)
- both ≤2/66 SJC plus CRP ≤8 mg/L
- Patient Evaluation of disease activity (Pt-VAS) ≥20 higher than Physician Evaluation of Disease Activity (MD-VAS).
Exclusion Criteria:
- Inability to consent (e.g. not fluent in French, dementia) or to participate in groups;
- Active vasculitis, SJC ≥3, CRP ≥8, arthritis drug changes (i.e. addition or increase of DMARDs or biologics or oral corticosteroids) during the last 3 months
Sites / Locations
- Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Estrie - CHUS
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Intervention
Control
Mindfulness-Based Stress Reduction (MBSR) is a program intended to draw upon the group's shared experiences to facilitate the development of mindfulness. MBSR is offered in 2.5-h classes on a weekly basis for 8 consecutive weeks, with a retreat day in between classes 6 and 7. This day involves guided meditations, allowing for continuity in practice. Classes include specific exercises (e.g. identifying thoughts, emotions and body sensations associated with illness); these are then extended as homework and discussed in the subsequent class. The curriculum themes and content are arranged week by week to reflect these principles.
The control group will receive usual care, with no treatment restrictions. Treating physicians will be informed of CES-D results. Patients will be asked to fulfill the same clinical assessment and questionnaires, and to provide the same biosamples than those patients in the intervention.