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A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy (ATHENA)

Primary Purpose

Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer

Status
Active
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
Rucaparib
Nivolumab
Placebo Oral Tablet
Placebo IV Infusion
Sponsored by
pharmaand GmbH
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Epithelial Ovarian Cancer focused on measuring PARP inhibitor, PARPi, HRD, ATHENA, homologous recombination, DNA repair, LOH, DNA defect, DNA anomaly, Rucaparib, Nivolumab, PD-1, Immuno-, oncology, Tumor, mutational, burden, BRCA, First-line, Primary Therapy, Primary Treatment

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)FemaleDoes not accept healthy volunteers

Inclusion Criteria:

  • Newly diagnosed advanced (FIGO stage III-IV) epithelial ovarian, fallopian tube, or primary peritoneal cancer.
  • Completed cytoreductive surgery, including at least a bilateral salpingo-oophorectomy and partial omentectomy, either prior to chemotherapy (primary surgery) or following neoadjuvant chemotherapy (interval debulking)
  • Completed first-line platinum-based chemotherapy and surgery with a response, in the opinion of the Investigator
  • Sufficient tumor tissue for planned analysis
  • ECOG performance status of 0 or 1
  • Patients must be 20 years of age to consent in Japan, Taiwan and South Korea; in all other participating countries patients must be 18 years of age to consent

Exclusion Criteria:

  • Pure sarcomas or borderline tumors or mucinous tumors
  • Active second malignancy
  • Known central nervous system brain metastases
  • Any prior treatment for ovarian cancer, other than the first-line platinum regimen
  • Evidence of interstitial lung disease or active pneumonitis
  • Active, known or suspected autoimmune disease
  • Condition requiring active systemic treatment with either corticosteroids (>10 mg daily prednisone equivalent) or other immunosuppressive medications

Sites / Locations

  • Arizona Oncology Associates, PC - HAL
  • Arizona Oncology Associates, PC - HOPE
  • The University of Arizona Cancer Center
  • John Muir Clinical Research Center
  • UCLA Women's Health Clinical Research Unit
  • Kaiser Permanente Northern California
  • University of Colorado Cancer Center
  • Rocky Mountain Cancer Centers
  • Yale University
  • Florida Gynecologic Oncology
  • MD Anderson Cancer Center-Baptist
  • Baptist Health Medical Group Oncology, LLC
  • Florida Hospital
  • Northside Hospital
  • Augusta University
  • Rush University Medical Center
  • Dr. Sudarshan K. Sharma, Ltd - Gynecologic Oncology
  • Van le
  • Community Health Network
  • University of Iowa Hospitals
  • University of Kansas Cancer Center
  • University of Kentucky
  • Norton Cancer Institute
  • Ochsner Medical Center
  • Maine Medical Center
  • SKCCC at Johns Hopkins
  • Massachusetts General Hospital
  • Karmanos Cancer Institute
  • Metro Minnesota Community Oncology Research Consortium
  • Washington University School of Medicine
  • Women's Cancer Center of Nevada
  • MD Anderson Cancer Center at Cooper
  • Summit Medical Group
  • Women's Cancer Care Associates
  • Broome Oncology, LLC
  • Northwell Health Monter Cancer Center
  • New York University Medical Center
  • University of North Carolina
  • University of Cincinnati
  • Oncology Hematology Care, Inc
  • Cleveland Clinic
  • The Ohio State University
  • MD Anderson Cancer Center - Ohio Health
  • University of Oklahoma Health Science Center
  • Oklahoma Cancer Specialists and Research Institute
  • Oncology Associates of Oregon, P.C.
  • LMG Gynecologic Oncology
  • Northwest Cancer Specialists, P.C.
  • University of Pennsylvania
  • Thomas Jefferson University
  • UPMC Magee-Womens Hospital
  • Abington Memorial Hospital
  • Avera Gynecologic Oncology
  • Texas Oncology - Austin Central
  • Texas Oncology - Bedford
  • Texas Oncology - Dallas Presbyterian Hospital
  • Texas Oncology - Fort Worth
  • Memorial Hermann
  • University of Texas MD Anderson Cancer Center
  • Texas Oncology - San Antonio Medical Center
  • Texas Oncology - The Woodlands, Gynecologic Oncology
  • Huntsman Cancer Institute
  • Virginia Oncology Associates
  • Froedtert and Medical College of Wisconsin
  • Newcastle Private Hospital
  • Northern Cancer Institute St Leonards
  • Prince of Wales Hospital
  • Westmead Hospital
  • Royal Brisbane and Women's Hospital
  • Brian Fricker Oncology Centre, Burnside Hospital
  • Peter MacCallum Cancer Center
  • St John of God Subiaco Hospital
  • UZ Leven
  • Alberta Health Services - University of Calgary
  • Alberta Health Services and The University of Alberta
  • BC Cancer - Abbotsford
  • BC Cancer - Kelowna
  • BC Cancer - Surrey
  • CancerCare Manitoba
  • Nsha-Qeii Hsc
  • Juravinski Cancer Center
  • London Health Sciences Center
  • Ottawa Hospital Cancer Centre
  • Centre Hospitalier de l'Université de Montreal
  • McGill University Health Center
  • Centre Integre Universitaire de sante et de service sociaux de l'Estri-Centre hospitalier univeritaire de Sherbrooke
  • Masaryk Memorial Cancer Institute
  • Department of Gynecology and Obstetrics, Oncogynecological center U hiversity Hospital Kralovske Vinohrady
  • KOC KNTB a.s. Zlfn, Hvalfckovo nabrezf 600, 76001
  • Aalborg University Hospital
  • Odense University Hospital
  • Kuopio University Hospital
  • Klinik für Frauenheilkunde und Geburtshilfe
  • Universitaetsklinikum Duesseldorf / Klinik fur Frauenheilkunde & Geburtshilfe
  • Universitatsklinikum National Centrum for Tumor Disease (NCT)
  • Universitätslinikum Mannheim, Frauenklinik
  • Kliniken Suedostbayern AG, Klinikum Traunstein
  • Attikon General University Hospital
  • University Hospital Attikon
  • Alexandra Hospital
  • General Hospital of Patras
  • Euromedica General Clinic, B' Oncology Clinic
  • Cork University Hospital
  • Bon Secours Hospital
  • University Hospital Limerick
  • University Hospital Waterford
  • Shaare Zedek Medical Oncology
  • Meir Medical Center
  • Galilee Medical Center
  • Sheba Medical Center
  • Ziv Medical Center
  • Tel Aviv Sourasky Medical Center
  • Centro di Riferimento Oncologico, CRO-IRCCS
  • Candiolo Cancer Institute - IRCCS
  • Arnas Garibaldi
  • University G, D'Annunuzio-Chieti
  • IRCCS Instituto Nazionale Tumori
  • Azienda Ospedaliera Universitaria Policlinico Umberto I
  • Policlinico Agostino Gemelli
  • Ospedale S. Giovanni Calibita Fatebenefratelli
  • Ospedale San Bortolo
  • University of Tsukuba Hospital
  • National Cancer Center Hospital East
  • Kurume University Hospital
  • Yokohama City University Hospital
  • Gunma University Hospital
  • Gunma Prefectural Cancer Center
  • Hiroshima City Hiroshima Citizens Hospital
  • Hyogo Cancer Center
  • Iwate Medical University
  • Nippon Medical School Musashikosugi Hospital
  • Kanagawa Cancer Center
  • National Defense Medical College Hospital
  • Osaka International Cancer Institute
  • Kindai University Hospital
  • Saitama Medical University International Medical Center
  • Keio University Hospital
  • The Cancer Institute Hospital of JFCR
  • Saitama Cancer Center
  • Kagawa Prefectural Central Hospital
  • National Cancer Center Hospital
  • National Cancer Center
  • Seoul National University Bundang Hospital
  • CHA Bundang Medical Center
  • Gachon University Gil Medical Center
  • SoonChunHyang Univeristy Cheonan Hosptial
  • Korea Cancer Center Hospital
  • Seoul National University Hospital
  • Severance Hospital,Yonsei University Health System
  • Konkuk University Medical Center
  • Asan Medical Center
  • Samsung Medical Center
  • Korea University Guro Hospital
  • Ajou University Hospital
  • Auckland City Hospital
  • Christchurch Hospital
  • Waikato Hospital
  • Palmerston North Hospital
  • Tauranga Hospital
  • Chair & department of Obsterics, Gynaecology and Oncology (previous site)
  • Bialostockie Centrum Onkologii Oddzial Onkologii Ginekologicznej
  • University Hospital of Bialystok
  • Szpitale Pomorskie sp zoo
  • Medical University of Lublin
  • Wielkopolskie Centrum Onkologii
  • Pomeranian Medical University
  • Spitalul Clinic Municipal "Dr. Gavril Curteanu"
  • S.C. Medisprof S.R.L.
  • Oncopremium Team
  • SC Quantum Medical Center SRL
  • Instiute of Oncology - Medical Oncology
  • Centrul de Oncologie Sf.Nectarie
  • S.C Oncolab S.R.L
  • Institutul Regional de Oncologie Iasi
  • Spital Municipal Ploiesti
  • Spitalul Judetean de Urgenta "Sfantul Ioan cel Nou" Suceava
  • ONCOMED Timisoara
  • Arkhangelsk Clinical Oncological Dispensary
  • BHI of Omsk Region Clinical Oncology Dispensary
  • Orenburg Regional Clinical Oncological Dispensary
  • SBHI Saint Petersburg Research Center specialized types of medical care (Oncology)
  • SBHI SR Pyatigorsk Interdistrict Oncology Dispensary
  • Limited Liability Company MedPomosch
  • FSBEI HE I.P. Pavlov SPbSMU MoH Russia
  • Saint-Petersburg State Budget Institution of Healthcare City Clinical Oncology Dispensary
  • 1st Medical University
  • Federa; State Budgetary Educational Institution of Higher Education National Research Ogarev Mordovia State University
  • State Medical Institution "Oncology Center #2" under the Krasnodar Region Healthcare Department
  • National University Hospital
  • National Cancer Center Singapore
  • Vall d'Hebron Institute of Oncology
  • Hospital de la Santa Creu i Sant Pau
  • Hospital Universitario Basurto
  • Consorcio Hospitalario Provincial Castellon
  • Hospital Virgen de la Arrixaca
  • Hospital de Jerez
  • Hospital Universitario Puerta de Hierro - Majadahonda
  • Hospital Universitario Central de Asturias
  • Hospital Son Llatzer
  • Hospital Nuestra Señora de Valme
  • Onkologiska Kliniken
  • Onkologiska Kliniken
  • Karolinska Universitetssjukhuset
  • Hualien Tzu Chi Hospital
  • Kaohsiung Veterans General Hospital
  • Far Eastern Memorial Hospital
  • Taichung Veterans General Hospital
  • China Medical University Hospital
  • Chi Mei Hospital, Liouying (CMHLY)
  • Chi Mei Medical Center (CMMC)
  • National Taiwan University Hospital
  • Mackay Memorial Hospital
  • Taipei Veterans General Hospital
  • Tri-Service General Hospital
  • Taipei Medical Univeristy Hopsital
  • Chang Gung Medical Foundation- Linkou Branch
  • Dr. Abdurrahman Yurtaslan Ankara Women's Health Education and Research Hospital
  • Istanbul University-cerrahpasa, Cerrahpasa School of Medicine
  • Koc University School of Medicine, Koc University Hospital
  • Celal Bayar University Faculty of Medicine
  • Baskent University Hospital
  • East Kent Hospitals University NHS Foundation trust Medical Oncology
  • Northampton General Hospital
  • Royal Sussex County Hospital
  • Bristol Cancer Institute Medical Oncology
  • Addenbrookes Hospital
  • Western General Hospital
  • University Hospitals of Morecambe Bay NHS Foundation Trust
  • St. James University Hospital
  • Barts and the London NHS Trust
  • University of College London Hospital
  • Guy's & St Thomas' NHS Foundation Trust (Guy's Cancer Centre)
  • The Royal Marsden NHS Foundation Trust
  • Imperial College London
  • The James Cook University Hospital
  • Poole Hospital NHS Foundation Trust
  • South West Wales Cancer Centre - Singleton Hospital
  • Musgrove Park Hospital

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Experimental

Experimental

Experimental

Placebo Comparator

Arm Label

Arm A

Arm B

Arm C

Arm D

Arm Description

oral rucaparib + intravenous (IV) nivolumab

oral rucaparib+IV placebo

oral placebo+ IV nivolumab

Oral placebo + IV placebo

Outcomes

Primary Outcome Measures

Investigator assessed Progression-free survival (PFS)

Secondary Outcome Measures

Blinded independent central review (BICR) PFS
Overall Survival (OS)
Objective response rate (ORR)
Duration of response (DOR)
Number of participants with treatment-emergent Adverse Events (AEs) as assessed by CTCAE v4 (or higher) as a measure of safety and tolerability
Number of participants with serious AEs as a measure of safety and tolerability
Number of participants with laboratory abnormalities as a measure of safety and tolerability

Full Information

First Posted
April 9, 2018
Last Updated
September 14, 2023
Sponsor
pharmaand GmbH
Collaborators
Bristol-Myers Squibb, Gynecologic Oncology Group, European Network of Gynaecological Oncological Trial Groups (ENGOT), Foundation Medicine
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1. Study Identification

Unique Protocol Identification Number
NCT03522246
Brief Title
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
Acronym
ATHENA
Official Title
ATHENA (A Multicenter, Randomized, Double-Blind, Placebo- Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy)
Study Type
Interventional

2. Study Status

Record Verification Date
September 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
May 14, 2018 (Actual)
Primary Completion Date
December 30, 2024 (Anticipated)
Study Completion Date
December 30, 2030 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
pharmaand GmbH
Collaborators
Bristol-Myers Squibb, Gynecologic Oncology Group, European Network of Gynaecological Oncological Trial Groups (ENGOT), Foundation Medicine

4. Oversight

Studies a U.S. FDA-regulated Drug Product
Yes
Studies a U.S. FDA-regulated Device Product
No
Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This is a Phase 3, randomized, multinational, double-blind, dual placebo-controlled, 4-arm study evaluating rucaparib and nivolumab as maintenance treatment following response to front-line treatment in newly diagnosed ovarian cancer patients. Response to treatment will be analyzed based on homologous recombination (HR) status of tumor samples.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Newly Diagnosed, FIGO Stage III-IV, Partial Response, Complete Response
Keywords
PARP inhibitor, PARPi, HRD, ATHENA, homologous recombination, DNA repair, LOH, DNA defect, DNA anomaly, Rucaparib, Nivolumab, PD-1, Immuno-, oncology, Tumor, mutational, burden, BRCA, First-line, Primary Therapy, Primary Treatment

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Masking Description
Double-Blind
Allocation
Randomized
Enrollment
1000 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Arm A
Arm Type
Experimental
Arm Description
oral rucaparib + intravenous (IV) nivolumab
Arm Title
Arm B
Arm Type
Experimental
Arm Description
oral rucaparib+IV placebo
Arm Title
Arm C
Arm Type
Experimental
Arm Description
oral placebo+ IV nivolumab
Arm Title
Arm D
Arm Type
Placebo Comparator
Arm Description
Oral placebo + IV placebo
Intervention Type
Drug
Intervention Name(s)
Rucaparib
Other Intervention Name(s)
Rubraca, CO-338
Intervention Description
Oral rucaparib will be administered twice daily
Intervention Type
Drug
Intervention Name(s)
Nivolumab
Other Intervention Name(s)
Opdivo, BMS-936558
Intervention Description
IV nivolumab will be administered once every 4 weeks
Intervention Type
Drug
Intervention Name(s)
Placebo Oral Tablet
Intervention Description
Placebo tablets will be administered twice daily
Intervention Type
Drug
Intervention Name(s)
Placebo IV Infusion
Intervention Description
IV placebo will be administered once every 4 weeks
Primary Outcome Measure Information:
Title
Investigator assessed Progression-free survival (PFS)
Time Frame
From randomization until disease progression (up to approximately 7 years)
Secondary Outcome Measure Information:
Title
Blinded independent central review (BICR) PFS
Time Frame
Every ~12 weeks after the start of combination treatment for ~3 years, then every ~24 weeks thereafter until disease progression. Study data collection expected to last for ~7 years
Title
Overall Survival (OS)
Time Frame
From enrollment to primary study completion of study (up to approximately 10 years)
Title
Objective response rate (ORR)
Time Frame
For patients with measurable disease, every ~12 weeks after the start of combination treatment for ~3 years, then every ~24 weeks thereafter until disease progression. Study data collection expected to last for ~7 years
Title
Duration of response (DOR)
Time Frame
For patients with measurable disease, every ~12 weeks after the start of combination treatment for ~3 years, then every ~24 weeks thereafter until disease progression. Study data collection expected to last for ~7 years
Title
Number of participants with treatment-emergent Adverse Events (AEs) as assessed by CTCAE v4 (or higher) as a measure of safety and tolerability
Time Frame
Collected from the time patient receives first dose of study drug until post treatment safety follow-up period (up to approximately 10 years)
Title
Number of participants with serious AEs as a measure of safety and tolerability
Time Frame
Collected from the time patient receives first dose of study drug until post treatment safety follow-up period (up to approximately 10 years)
Title
Number of participants with laboratory abnormalities as a measure of safety and tolerability
Time Frame
Collected from the time patient receives first dose of study drug until post treatment safety follow-up period (up to approximately 10 years)

10. Eligibility

Sex
Female
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Newly diagnosed advanced (FIGO stage III-IV) epithelial ovarian, fallopian tube, or primary peritoneal cancer. Completed cytoreductive surgery, including at least a bilateral salpingo-oophorectomy and partial omentectomy, either prior to chemotherapy (primary surgery) or following neoadjuvant chemotherapy (interval debulking) Completed first-line platinum-based chemotherapy and surgery with a response, in the opinion of the Investigator Sufficient tumor tissue for planned analysis ECOG performance status of 0 or 1 Patients must be 20 years of age to consent in Japan, Taiwan and South Korea; in all other participating countries patients must be 18 years of age to consent Exclusion Criteria: Pure sarcomas or borderline tumors or mucinous tumors Active second malignancy Known central nervous system brain metastases Any prior treatment for ovarian cancer, other than the first-line platinum regimen Evidence of interstitial lung disease or active pneumonitis Active, known or suspected autoimmune disease Condition requiring active systemic treatment with either corticosteroids (>10 mg daily prednisone equivalent) or other immunosuppressive medications
Facility Information:
Facility Name
Arizona Oncology Associates, PC - HAL
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85016
Country
United States
Facility Name
Arizona Oncology Associates, PC - HOPE
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85711
Country
United States
Facility Name
The University of Arizona Cancer Center
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
John Muir Clinical Research Center
City
Concord
State/Province
California
ZIP/Postal Code
94520
Country
United States
Facility Name
UCLA Women's Health Clinical Research Unit
City
Los Angeles
State/Province
California
ZIP/Postal Code
90095
Country
United States
Facility Name
Kaiser Permanente Northern California
City
San Francisco
State/Province
California
ZIP/Postal Code
94589
Country
United States
Facility Name
University of Colorado Cancer Center
City
Aurora
State/Province
Colorado
ZIP/Postal Code
80045
Country
United States
Facility Name
Rocky Mountain Cancer Centers
City
Lakewood
State/Province
Colorado
ZIP/Postal Code
80228
Country
United States
Facility Name
Yale University
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06520
Country
United States
Facility Name
Florida Gynecologic Oncology
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33905
Country
United States
Facility Name
MD Anderson Cancer Center-Baptist
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32207
Country
United States
Facility Name
Baptist Health Medical Group Oncology, LLC
City
Miami
State/Province
Florida
ZIP/Postal Code
33176
Country
United States
Facility Name
Florida Hospital
City
Orlando
State/Province
Florida
ZIP/Postal Code
32804
Country
United States
Facility Name
Northside Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Facility Name
Augusta University
City
Augusta
State/Province
Georgia
ZIP/Postal Code
30912
Country
United States
Facility Name
Rush University Medical Center
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60612
Country
United States
Facility Name
Dr. Sudarshan K. Sharma, Ltd - Gynecologic Oncology
City
Hinsdale
State/Province
Illinois
ZIP/Postal Code
60521
Country
United States
Facility Name
Van le
City
Springfield
State/Province
Illinois
ZIP/Postal Code
62769
Country
United States
Facility Name
Community Health Network
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46250
Country
United States
Facility Name
University of Iowa Hospitals
City
Iowa City
State/Province
Iowa
ZIP/Postal Code
52242
Country
United States
Facility Name
University of Kansas Cancer Center
City
Westwood
State/Province
Kansas
ZIP/Postal Code
66205
Country
United States
Facility Name
University of Kentucky
City
Lexington
State/Province
Kentucky
ZIP/Postal Code
40536
Country
United States
Facility Name
Norton Cancer Institute
City
Louisville
State/Province
Kentucky
ZIP/Postal Code
40241
Country
United States
Facility Name
Ochsner Medical Center
City
New Orleans
State/Province
Louisiana
ZIP/Postal Code
70121
Country
United States
Facility Name
Maine Medical Center
City
Scarborough
State/Province
Maine
ZIP/Postal Code
04074
Country
United States
Facility Name
SKCCC at Johns Hopkins
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Facility Name
Massachusetts General Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02114
Country
United States
Facility Name
Karmanos Cancer Institute
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48201
Country
United States
Facility Name
Metro Minnesota Community Oncology Research Consortium
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
Washington University School of Medicine
City
Saint Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Facility Name
Women's Cancer Center of Nevada
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89169
Country
United States
Facility Name
MD Anderson Cancer Center at Cooper
City
Camden
State/Province
New Jersey
ZIP/Postal Code
08103
Country
United States
Facility Name
Summit Medical Group
City
Florham Park
State/Province
New Jersey
ZIP/Postal Code
07932
Country
United States
Facility Name
Women's Cancer Care Associates
City
Albany
State/Province
New York
ZIP/Postal Code
12008
Country
United States
Facility Name
Broome Oncology, LLC
City
Johnson City
State/Province
New York
ZIP/Postal Code
13790
Country
United States
Facility Name
Northwell Health Monter Cancer Center
City
Lake Success
State/Province
New York
ZIP/Postal Code
11042
Country
United States
Facility Name
New York University Medical Center
City
New York
State/Province
New York
ZIP/Postal Code
10016
Country
United States
Facility Name
University of North Carolina
City
Chapel Hill
State/Province
North Carolina
ZIP/Postal Code
27707
Country
United States
Facility Name
University of Cincinnati
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45221
Country
United States
Facility Name
Oncology Hematology Care, Inc
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45242
Country
United States
Facility Name
Cleveland Clinic
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44106
Country
United States
Facility Name
The Ohio State University
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43210
Country
United States
Facility Name
MD Anderson Cancer Center - Ohio Health
City
Columbus
State/Province
Ohio
ZIP/Postal Code
44907
Country
United States
Facility Name
University of Oklahoma Health Science Center
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
Oklahoma Cancer Specialists and Research Institute
City
Tulsa
State/Province
Oklahoma
ZIP/Postal Code
74146
Country
United States
Facility Name
Oncology Associates of Oregon, P.C.
City
Eugene
State/Province
Oregon
ZIP/Postal Code
97401
Country
United States
Facility Name
LMG Gynecologic Oncology
City
Portland
State/Province
Oregon
ZIP/Postal Code
97210
Country
United States
Facility Name
Northwest Cancer Specialists, P.C.
City
Portland
State/Province
Oregon
ZIP/Postal Code
97225
Country
United States
Facility Name
University of Pennsylvania
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
Thomas Jefferson University
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19107
Country
United States
Facility Name
UPMC Magee-Womens Hospital
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15213
Country
United States
Facility Name
Abington Memorial Hospital
City
Willow Grove
State/Province
Pennsylvania
ZIP/Postal Code
19090
Country
United States
Facility Name
Avera Gynecologic Oncology
City
Sioux Falls
State/Province
South Dakota
ZIP/Postal Code
57105
Country
United States
Facility Name
Texas Oncology - Austin Central
City
Austin
State/Province
Texas
ZIP/Postal Code
78731
Country
United States
Facility Name
Texas Oncology - Bedford
City
Bedford
State/Province
Texas
ZIP/Postal Code
76022
Country
United States
Facility Name
Texas Oncology - Dallas Presbyterian Hospital
City
Dallas
State/Province
Texas
ZIP/Postal Code
75231
Country
United States
Facility Name
Texas Oncology - Fort Worth
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Facility Name
Memorial Hermann
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
University of Texas MD Anderson Cancer Center
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
Texas Oncology - San Antonio Medical Center
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78240
Country
United States
Facility Name
Texas Oncology - The Woodlands, Gynecologic Oncology
City
The Woodlands
State/Province
Texas
ZIP/Postal Code
77380
Country
United States
Facility Name
Huntsman Cancer Institute
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84112
Country
United States
Facility Name
Virginia Oncology Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Froedtert and Medical College of Wisconsin
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Newcastle Private Hospital
City
New Lambton Heights
State/Province
New South Wales
ZIP/Postal Code
2145
Country
Australia
Facility Name
Northern Cancer Institute St Leonards
City
Saint Leonards
State/Province
New South Wales
ZIP/Postal Code
2065
Country
Australia
Facility Name
Prince of Wales Hospital
City
Sydney
State/Province
New South Wales
ZIP/Postal Code
2031
Country
Australia
Facility Name
Westmead Hospital
City
Westmead
State/Province
New South Wales
ZIP/Postal Code
2145
Country
Australia
Facility Name
Royal Brisbane and Women's Hospital
City
Brisbane
State/Province
Queensland
ZIP/Postal Code
4020
Country
Australia
Facility Name
Brian Fricker Oncology Centre, Burnside Hospital
City
Toorak Gardens
State/Province
South Australia
ZIP/Postal Code
5065
Country
Australia
Facility Name
Peter MacCallum Cancer Center
City
Melbourne
State/Province
Victoria
ZIP/Postal Code
3000
Country
Australia
Facility Name
St John of God Subiaco Hospital
City
Subiaco
State/Province
Western Australia
ZIP/Postal Code
6005
Country
Australia
Facility Name
UZ Leven
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
Facility Name
Alberta Health Services - University of Calgary
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N 1N4
Country
Canada
Facility Name
Alberta Health Services and The University of Alberta
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 2B7
Country
Canada
Facility Name
BC Cancer - Abbotsford
City
Abbotsford
State/Province
British Columbia
ZIP/Postal Code
V2S 0C2
Country
Canada
Facility Name
BC Cancer - Kelowna
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 5L3
Country
Canada
Facility Name
BC Cancer - Surrey
City
Surrey
State/Province
British Columbia
ZIP/Postal Code
V3V 1Z2
Country
Canada
Facility Name
CancerCare Manitoba
City
Winnipeg
State/Province
Manitoba
ZIP/Postal Code
R3E 0V9
Country
Canada
Facility Name
Nsha-Qeii Hsc
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H 2Y9
Country
Canada
Facility Name
Juravinski Cancer Center
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
LbV 5C2
Country
Canada
Facility Name
London Health Sciences Center
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 5W9
Country
Canada
Facility Name
Ottawa Hospital Cancer Centre
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 8L6
Country
Canada
Facility Name
Centre Hospitalier de l'Université de Montreal
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H2X 0C2
Country
Canada
Facility Name
McGill University Health Center
City
Montréal
State/Province
Quebec
ZIP/Postal Code
H4A 3J1
Country
Canada
Facility Name
Centre Integre Universitaire de sante et de service sociaux de l'Estri-Centre hospitalier univeritaire de Sherbrooke
City
Sherbrooke
State/Province
Quebec
ZIP/Postal Code
J1H 5N4
Country
Canada
Facility Name
Masaryk Memorial Cancer Institute
City
Brno
ZIP/Postal Code
65653
Country
Czechia
Facility Name
Department of Gynecology and Obstetrics, Oncogynecological center U hiversity Hospital Kralovske Vinohrady
City
Prague
Country
Czechia
Facility Name
KOC KNTB a.s. Zlfn, Hvalfckovo nabrezf 600, 76001
City
Zlín
Country
Czechia
Facility Name
Aalborg University Hospital
City
Aalborg
ZIP/Postal Code
9000
Country
Denmark
Facility Name
Odense University Hospital
City
Odense
ZIP/Postal Code
5000
Country
Denmark
Facility Name
Kuopio University Hospital
City
Kuopio
ZIP/Postal Code
70210
Country
Finland
Facility Name
Klinik für Frauenheilkunde und Geburtshilfe
City
Dessau
Country
Germany
Facility Name
Universitaetsklinikum Duesseldorf / Klinik fur Frauenheilkunde & Geburtshilfe
City
Duesseldorf
Country
Germany
Facility Name
Universitatsklinikum National Centrum for Tumor Disease (NCT)
City
Heidelberg
Country
Germany
Facility Name
Universitätslinikum Mannheim, Frauenklinik
City
Mannheim
Country
Germany
Facility Name
Kliniken Suedostbayern AG, Klinikum Traunstein
City
Traunstein
Country
Germany
Facility Name
Attikon General University Hospital
City
Chaidari
State/Province
Athens
ZIP/Postal Code
12462
Country
Greece
Facility Name
University Hospital Attikon
City
Chaidari
State/Province
Athens
ZIP/Postal Code
12462
Country
Greece
Facility Name
Alexandra Hospital
City
Athens
ZIP/Postal Code
11528
Country
Greece
Facility Name
General Hospital of Patras
City
Patra
ZIP/Postal Code
26335
Country
Greece
Facility Name
Euromedica General Clinic, B' Oncology Clinic
City
Thessaloniki
ZIP/Postal Code
5465
Country
Greece
Facility Name
Cork University Hospital
City
Cork
ZIP/Postal Code
T12 DC4A
Country
Ireland
Facility Name
Bon Secours Hospital
City
Cork
Country
Ireland
Facility Name
University Hospital Limerick
City
Limerick
ZIP/Postal Code
V94 F858
Country
Ireland
Facility Name
University Hospital Waterford
City
Waterford
ZIP/Postal Code
X91 ER8E
Country
Ireland
Facility Name
Shaare Zedek Medical Oncology
City
Jerusalem
Country
Israel
Facility Name
Meir Medical Center
City
Kfar Saba
ZIP/Postal Code
4428164
Country
Israel
Facility Name
Galilee Medical Center
City
Nahariya
ZIP/Postal Code
2210001
Country
Israel
Facility Name
Sheba Medical Center
City
Ramat Gan
ZIP/Postal Code
5265601
Country
Israel
Facility Name
Ziv Medical Center
City
Safed
ZIP/Postal Code
13100
Country
Israel
Facility Name
Tel Aviv Sourasky Medical Center
City
Tel Aviv
ZIP/Postal Code
6423906
Country
Israel
Facility Name
Centro di Riferimento Oncologico, CRO-IRCCS
City
Aviano
ZIP/Postal Code
33081
Country
Italy
Facility Name
Candiolo Cancer Institute - IRCCS
City
Candiolo
ZIP/Postal Code
10060
Country
Italy
Facility Name
Arnas Garibaldi
City
Catania
ZIP/Postal Code
95122
Country
Italy
Facility Name
University G, D'Annunuzio-Chieti
City
Chieti
Country
Italy
Facility Name
IRCCS Instituto Nazionale Tumori
City
Napoli
ZIP/Postal Code
80131
Country
Italy
Facility Name
Azienda Ospedaliera Universitaria Policlinico Umberto I
City
Roma
ZIP/Postal Code
00161
Country
Italy
Facility Name
Policlinico Agostino Gemelli
City
Roma
ZIP/Postal Code
00168
Country
Italy
Facility Name
Ospedale S. Giovanni Calibita Fatebenefratelli
City
Roma
ZIP/Postal Code
00186
Country
Italy
Facility Name
Ospedale San Bortolo
City
Vicenza
ZIP/Postal Code
36100
Country
Italy
Facility Name
University of Tsukuba Hospital
City
Tsukuba
State/Province
Amakubo
Country
Japan
Facility Name
National Cancer Center Hospital East
City
Kashiwa
State/Province
Chiba
ZIP/Postal Code
277-8577
Country
Japan
Facility Name
Kurume University Hospital
City
Kurume
State/Province
Fukuoka
ZIP/Postal Code
830-0011
Country
Japan
Facility Name
Yokohama City University Hospital
City
Yokohama
State/Province
Fukuura
Country
Japan
Facility Name
Gunma University Hospital
City
Maebashi
State/Province
Gunma
ZIP/Postal Code
371-8511
Country
Japan
Facility Name
Gunma Prefectural Cancer Center
City
Ota-shi
State/Province
Gunma
ZIP/Postal Code
373-8550
Country
Japan
Facility Name
Hiroshima City Hiroshima Citizens Hospital
City
Naka
State/Province
Hiroshima
ZIP/Postal Code
730-0844,
Country
Japan
Facility Name
Hyogo Cancer Center
City
Akashi
State/Province
Hyogo
ZIP/Postal Code
673-0021
Country
Japan
Facility Name
Iwate Medical University
City
Morioka
State/Province
Iwate
Country
Japan
Facility Name
Nippon Medical School Musashikosugi Hospital
City
Kawasaki-shi
State/Province
Kanagawa
ZIP/Postal Code
211-8533
Country
Japan
Facility Name
Kanagawa Cancer Center
City
Yokohama
State/Province
Kanagawa
ZIP/Postal Code
241-8515
Country
Japan
Facility Name
National Defense Medical College Hospital
City
Tokorozawa
State/Province
Namiki
Country
Japan
Facility Name
Osaka International Cancer Institute
City
Chuo
State/Province
Osaka
ZIP/Postal Code
541-8567
Country
Japan
Facility Name
Kindai University Hospital
City
Ōsaka-sayama
State/Province
Osaka
ZIP/Postal Code
589-8511
Country
Japan
Facility Name
Saitama Medical University International Medical Center
City
Hidaka
State/Province
Saitama
ZIP/Postal Code
350-1298
Country
Japan
Facility Name
Keio University Hospital
City
Shinjuku-Ku
State/Province
Shinanomachi
Country
Japan
Facility Name
The Cancer Institute Hospital of JFCR
City
Koto-Ku
State/Province
Tokyo
Country
Japan
Facility Name
Saitama Cancer Center
City
Saitama
ZIP/Postal Code
362-0806
Country
Japan
Facility Name
Kagawa Prefectural Central Hospital
City
Takamatsu
Country
Japan
Facility Name
National Cancer Center Hospital
City
Tokyo
ZIP/Postal Code
104-0045
Country
Japan
Facility Name
National Cancer Center
City
Goyang-si
State/Province
Gyeonggi-do
ZIP/Postal Code
10408
Country
Korea, Republic of
Facility Name
Seoul National University Bundang Hospital
City
Seongnam-si
State/Province
Gyeonggi-do
ZIP/Postal Code
13620
Country
Korea, Republic of
Facility Name
CHA Bundang Medical Center
City
Seongnam
State/Province
Gyeonggi-do
ZIP/Postal Code
13496
Country
Korea, Republic of
Facility Name
Gachon University Gil Medical Center
City
Incheon
State/Province
Seoul
ZIP/Postal Code
21565
Country
Korea, Republic of
Facility Name
SoonChunHyang Univeristy Cheonan Hosptial
City
Cheonan
Country
Korea, Republic of
Facility Name
Korea Cancer Center Hospital
City
Seoul
ZIP/Postal Code
01812
Country
Korea, Republic of
Facility Name
Seoul National University Hospital
City
Seoul
ZIP/Postal Code
03080
Country
Korea, Republic of
Facility Name
Severance Hospital,Yonsei University Health System
City
Seoul
ZIP/Postal Code
03722
Country
Korea, Republic of
Facility Name
Konkuk University Medical Center
City
Seoul
ZIP/Postal Code
05030
Country
Korea, Republic of
Facility Name
Asan Medical Center
City
Seoul
ZIP/Postal Code
05505
Country
Korea, Republic of
Facility Name
Samsung Medical Center
City
Seoul
ZIP/Postal Code
06351
Country
Korea, Republic of
Facility Name
Korea University Guro Hospital
City
Seoul
Country
Korea, Republic of
Facility Name
Ajou University Hospital
City
Suwon-si
Country
Korea, Republic of
Facility Name
Auckland City Hospital
City
Auckland
ZIP/Postal Code
1023
Country
New Zealand
Facility Name
Christchurch Hospital
City
Christchurch
ZIP/Postal Code
8011
Country
New Zealand
Facility Name
Waikato Hospital
City
Hamilton
ZIP/Postal Code
3204
Country
New Zealand
Facility Name
Palmerston North Hospital
City
Palmerston North
ZIP/Postal Code
4442
Country
New Zealand
Facility Name
Tauranga Hospital
City
Tauranga
ZIP/Postal Code
3112
Country
New Zealand
Facility Name
Chair & department of Obsterics, Gynaecology and Oncology (previous site)
City
Warsaw
State/Province
Kondratowicza
Country
Poland
Facility Name
Bialostockie Centrum Onkologii Oddzial Onkologii Ginekologicznej
City
Bialystok
ZIP/Postal Code
20-081
Country
Poland
Facility Name
University Hospital of Bialystok
City
Białystok
Country
Poland
Facility Name
Szpitale Pomorskie sp zoo
City
Gdynia
ZIP/Postal Code
81-519
Country
Poland
Facility Name
Medical University of Lublin
City
Lublin
ZIP/Postal Code
20-081
Country
Poland
Facility Name
Wielkopolskie Centrum Onkologii
City
Poznań
ZIP/Postal Code
61-866
Country
Poland
Facility Name
Pomeranian Medical University
City
Szczecin
Country
Poland
Facility Name
Spitalul Clinic Municipal "Dr. Gavril Curteanu"
City
Oradea
State/Province
Jud. Bihor
ZIP/Postal Code
410469
Country
Romania
Facility Name
S.C. Medisprof S.R.L.
City
Cluj-Napoca
State/Province
Jud. Cluj
ZIP/Postal Code
400641
Country
Romania
Facility Name
Oncopremium Team
City
Baia Mare
Country
Romania
Facility Name
SC Quantum Medical Center SRL
City
Bucuresti
Country
Romania
Facility Name
Instiute of Oncology - Medical Oncology
City
Cluj-Napoca
Country
Romania
Facility Name
Centrul de Oncologie Sf.Nectarie
City
Craiova
ZIP/Postal Code
200347
Country
Romania
Facility Name
S.C Oncolab S.R.L
City
Craiova
Country
Romania
Facility Name
Institutul Regional de Oncologie Iasi
City
Iaşi
ZIP/Postal Code
700489
Country
Romania
Facility Name
Spital Municipal Ploiesti
City
Ploieşti
Country
Romania
Facility Name
Spitalul Judetean de Urgenta "Sfantul Ioan cel Nou" Suceava
City
Suceava
ZIP/Postal Code
720237
Country
Romania
Facility Name
ONCOMED Timisoara
City
Timişoara
ZIP/Postal Code
300239
Country
Romania
Facility Name
Arkhangelsk Clinical Oncological Dispensary
City
Arkhangel'sk
ZIP/Postal Code
163045
Country
Russian Federation
Facility Name
BHI of Omsk Region Clinical Oncology Dispensary
City
Omsk
ZIP/Postal Code
644013
Country
Russian Federation
Facility Name
Orenburg Regional Clinical Oncological Dispensary
City
Orenburg
Country
Russian Federation
Facility Name
SBHI Saint Petersburg Research Center specialized types of medical care (Oncology)
City
Pesochnyy
ZIP/Postal Code
197758
Country
Russian Federation
Facility Name
SBHI SR Pyatigorsk Interdistrict Oncology Dispensary
City
Pyatigorsk
ZIP/Postal Code
357502
Country
Russian Federation
Facility Name
Limited Liability Company MedPomosch
City
Saint Petersburg
ZIP/Postal Code
194356
Country
Russian Federation
Facility Name
FSBEI HE I.P. Pavlov SPbSMU MoH Russia
City
Saint Petersburg
ZIP/Postal Code
197022
Country
Russian Federation
Facility Name
Saint-Petersburg State Budget Institution of Healthcare City Clinical Oncology Dispensary
City
Saint Petersburg
ZIP/Postal Code
198255
Country
Russian Federation
Facility Name
1st Medical University
City
Saint Petersburg
Country
Russian Federation
Facility Name
Federa; State Budgetary Educational Institution of Higher Education National Research Ogarev Mordovia State University
City
Saransk
ZIP/Postal Code
430032
Country
Russian Federation
Facility Name
State Medical Institution "Oncology Center #2" under the Krasnodar Region Healthcare Department
City
Sotchi
ZIP/Postal Code
354057
Country
Russian Federation
Facility Name
National University Hospital
City
Singapore
ZIP/Postal Code
119082
Country
Singapore
Facility Name
National Cancer Center Singapore
City
Singapore
Country
Singapore
Facility Name
Vall d'Hebron Institute of Oncology
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Facility Name
Hospital de la Santa Creu i Sant Pau
City
Barcelona
ZIP/Postal Code
08041
Country
Spain
Facility Name
Hospital Universitario Basurto
City
Bilbao
ZIP/Postal Code
48013
Country
Spain
Facility Name
Consorcio Hospitalario Provincial Castellon
City
Castillón
ZIP/Postal Code
12002
Country
Spain
Facility Name
Hospital Virgen de la Arrixaca
City
El Palmar
ZIP/Postal Code
30120
Country
Spain
Facility Name
Hospital de Jerez
City
Jerez de la Frontera
ZIP/Postal Code
11407
Country
Spain
Facility Name
Hospital Universitario Puerta de Hierro - Majadahonda
City
Madrid
ZIP/Postal Code
28222
Country
Spain
Facility Name
Hospital Universitario Central de Asturias
City
Oviedo
ZIP/Postal Code
33011
Country
Spain
Facility Name
Hospital Son Llatzer
City
Palma De Mallorca
ZIP/Postal Code
07198
Country
Spain
Facility Name
Hospital Nuestra Señora de Valme
City
Sevilla
ZIP/Postal Code
41014
Country
Spain
Facility Name
Onkologiska Kliniken
City
Linköping
Country
Sweden
Facility Name
Onkologiska Kliniken
City
Lund
Country
Sweden
Facility Name
Karolinska Universitetssjukhuset
City
Stockholm
Country
Sweden
Facility Name
Hualien Tzu Chi Hospital
City
Hualien City
Country
Taiwan
Facility Name
Kaohsiung Veterans General Hospital
City
Kaohsiung
ZIP/Postal Code
81362
Country
Taiwan
Facility Name
Far Eastern Memorial Hospital
City
New Taipei City
ZIP/Postal Code
22060
Country
Taiwan
Facility Name
Taichung Veterans General Hospital
City
Taichung
ZIP/Postal Code
40705
Country
Taiwan
Facility Name
China Medical University Hospital
City
Taichung
Country
Taiwan
Facility Name
Chi Mei Hospital, Liouying (CMHLY)
City
Tainan
Country
Taiwan
Facility Name
Chi Mei Medical Center (CMMC)
City
Tainan
Country
Taiwan
Facility Name
National Taiwan University Hospital
City
Taipei
ZIP/Postal Code
10048
Country
Taiwan
Facility Name
Mackay Memorial Hospital
City
Taipei
ZIP/Postal Code
10449
Country
Taiwan
Facility Name
Taipei Veterans General Hospital
City
Taipei
ZIP/Postal Code
11217
Country
Taiwan
Facility Name
Tri-Service General Hospital
City
Taipei
ZIP/Postal Code
11490
Country
Taiwan
Facility Name
Taipei Medical Univeristy Hopsital
City
Taipei
Country
Taiwan
Facility Name
Chang Gung Medical Foundation- Linkou Branch
City
Taoyuan
ZIP/Postal Code
33305
Country
Taiwan
Facility Name
Dr. Abdurrahman Yurtaslan Ankara Women's Health Education and Research Hospital
City
Ankara
Country
Turkey
Facility Name
Istanbul University-cerrahpasa, Cerrahpasa School of Medicine
City
Istanbul
Country
Turkey
Facility Name
Koc University School of Medicine, Koc University Hospital
City
Istanbul
Country
Turkey
Facility Name
Celal Bayar University Faculty of Medicine
City
Manisa
ZIP/Postal Code
45030
Country
Turkey
Facility Name
Baskent University Hospital
City
Yuregir
Country
Turkey
Facility Name
East Kent Hospitals University NHS Foundation trust Medical Oncology
City
Canterbury
State/Province
Kent
ZIP/Postal Code
CT1 3NG
Country
United Kingdom
Facility Name
Northampton General Hospital
City
Cliftonville
State/Province
Northampton
ZIP/Postal Code
NN1 5BD
Country
United Kingdom
Facility Name
Royal Sussex County Hospital
City
Brighton
ZIP/Postal Code
BN2 3EH
Country
United Kingdom
Facility Name
Bristol Cancer Institute Medical Oncology
City
Bristol
ZIP/Postal Code
BS2 8HW
Country
United Kingdom
Facility Name
Addenbrookes Hospital
City
Cambridge
ZIP/Postal Code
CB2 0QQ
Country
United Kingdom
Facility Name
Western General Hospital
City
Edinburgh
ZIP/Postal Code
EH4 2XU
Country
United Kingdom
Facility Name
University Hospitals of Morecambe Bay NHS Foundation Trust
City
Lancaster
ZIP/Postal Code
LA1 4RP
Country
United Kingdom
Facility Name
St. James University Hospital
City
Leeds
ZIP/Postal Code
LS9 7TF
Country
United Kingdom
Facility Name
Barts and the London NHS Trust
City
London
ZIP/Postal Code
EC1A 7BE
Country
United Kingdom
Facility Name
University of College London Hospital
City
London
ZIP/Postal Code
NW1 2PG
Country
United Kingdom
Facility Name
Guy's & St Thomas' NHS Foundation Trust (Guy's Cancer Centre)
City
London
ZIP/Postal Code
SE1 9RT
Country
United Kingdom
Facility Name
The Royal Marsden NHS Foundation Trust
City
London
ZIP/Postal Code
SW3 6JJ
Country
United Kingdom
Facility Name
Imperial College London
City
London
ZIP/Postal Code
W12 0HS
Country
United Kingdom
Facility Name
The James Cook University Hospital
City
Middlesbrough
ZIP/Postal Code
TS4 3BW
Country
United Kingdom
Facility Name
Poole Hospital NHS Foundation Trust
City
Poole
ZIP/Postal Code
BH15 2JB
Country
United Kingdom
Facility Name
South West Wales Cancer Centre - Singleton Hospital
City
Swansea
ZIP/Postal Code
SA2 8QA
Country
United Kingdom
Facility Name
Musgrove Park Hospital
City
Taunton
ZIP/Postal Code
TA1 5DA
Country
United Kingdom

12. IPD Sharing Statement

Citations:
PubMed Identifier
35658487
Citation
Monk BJ, Parkinson C, Lim MC, O'Malley DM, Oaknin A, Wilson MK, Coleman RL, Lorusso D, Bessette P, Ghamande S, Christopoulou A, Provencher D, Prendergast E, Demirkiran F, Mikheeva O, Yeku O, Chudecka-Glaz A, Schenker M, Littell RD, Safra T, Chou HH, Morgan MA, Drochytek V, Barlin JN, Van Gorp T, Ueland F, Lindahl G, Anderson C, Collins DC, Moore K, Marme F, Westin SN, McNeish IA, Shih D, Lin KK, Goble S, Hume S, Fujiwara K, Kristeleit RS. A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov45). J Clin Oncol. 2022 Dec 1;40(34):3952-3964. doi: 10.1200/JCO.22.01003. Epub 2022 Jun 6.
Results Reference
derived
PubMed Identifier
34593565
Citation
Monk BJ, Coleman RL, Fujiwara K, Wilson MK, Oza AM, Oaknin A, O'Malley DM, Lorusso D, Westin SN, Safra T, Herzog TJ, Marme F, N Eskander R, Lin KK, Shih D, Goble S, Grechko N, Hume S, Maloney L, McNeish IA, Kristeleit RS. ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA-MONO) and rucaparib in combination with nivolumab (ATHENA-COMBO) as maintenance treatment following frontline platinum-based chemotherapy in ovarian cancer. Int J Gynecol Cancer. 2021 Dec;31(12):1589-1594. doi: 10.1136/ijgc-2021-002933. Epub 2021 Sep 30.
Results Reference
derived

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A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy

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