Social Value Training in Toddlers With Elevated Autism Symptoms (SVT)
Autism Spectrum Disorder
About this trial
This is an interventional treatment trial for Autism Spectrum Disorder
Eligibility Criteria
Inclusion Criteria:
- Singleton pregnancy
- Gestational age of 37-42 weeks
- Appropriate weight for gestational age
- Presence of an older full biological sibling with ASD
- Autism Diagnostic Observation Schedule-2 (ADOS-2) score at 18 months in the clinical range (calibrated severity score >3)
Exclusion Criteria:
- Congenital infections
- Non-febrile seizure disorder
- Hearing loss
- Visual impairment
- Presence of any known chromosomal abnormality or congenital infection
- Prenatal exposure to illicit drugs
- Major psychotic disorder in first degree relatives.
Sites / Locations
- Yale University School of MedicineRecruiting
Arms of the Study
Arm 1
Experimental
Social Value Learning
For each child, two faces, randomly selected from the pool of four faces, will be assigned the high-value (HV) status and the other two the low-value (LV) status. Value status will be randomized between the faces and children and all four faces will have the same probability of being assigned HV or LV across all participants. A gaze fixation on a HV face will always activate a dynamic display and the face will smile brightly. A gaze fixation on a LV face will always result in no change to its display. Effects of training will be tested one day (efficacy) and one month (maintenance) after training. During each of the follow-up assessments, each child will first undergo the Laboratory Selective Attention (LSA) task to assess if they retained value-face associations from the training sessions, followed by the Real-World Selective Attention (RWSA) task to evaluate generalization.