Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia (HIT)
Hyponatremia
About this trial
This is an interventional treatment trial for Hyponatremia
Eligibility Criteria
Inclusion Criteria:
- All adult hospitalised patients with hypotonic hyponatremia <130mmol/L
Exclusion Criteria:
- severe symptomatic hyponatremia in need of intensive care treatment
- non-hypotonic hyponatremia with plasma osmolality >280 milliosmol (mOsm)/kg
- end of life care (palliative treatment)
Sites / Locations
- University Hospital Basel, Department of EndocrinologyRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Standard care plus targeted correction of hyponatremia
Standard care
Diagnosis and treatment of hyponatremia will be standardized according to the European Clinical Practice Guidelines (ECPG). Treatment response and adherence will be evaluated daily and treatment adapted if treatment goals are not reached.Targeted correction of plasma sodium Levels.
Diagnosis and treatment of hyponatremia will be solely at the discretion of the attending physicians who are in no way involved in the trial. The study team will not intervene with the treatment in any way. Diagnostic and treatment decisions as well as course of the plasma sodium level will only be recorded after patient is discharged from hospital using the medical records and patient charts. It will be generally recommended to measure plasma sodium levels 3x weekly or more frequently if clinically indicated, at discharge and after 30 days.