To Study the Effects of Lipid Emulsion on Hemodynamics in Organophosphate Compound Poisoning
Organophosphate Poisoning
About this trial
This is an interventional supportive care trial for Organophosphate Poisoning
Eligibility Criteria
Inclusion criteria
- History of consumption of OP compound.
- Symptom complex consistent with OP poisoning
- Age > 18 years
- Informed consent from the patient or next kin.
Exclusion criteria
- History of combined poisoning with a non OP compound.
- All other patients not fitting in the organophosphate symptom complex.
- Patients with underlying liver and kidney disease.
- History suggestive of acute pancreatitis in the past.
Sites / Locations
- Pgimer
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Study group
Historic controls
Inclusion criteria History of consumption of OP compound. Symptom complex consistent with OP poisoning Age > 18 years Informed consent from the patient or next kin. Exclusion criteria History of combined poisoning with a non OP compound. All other patients not fitting in the organophosphate symptom complex. Patients with underlying liver and kidney disease. History suggestive of acute pancreatitis in the past. All patients with history and clinical features of OP compound poisoning admitted to the emergency department in PGIMER during the study period, meeting the inclusion, exclusion criteria and who gave consent were enrolled in the study. Intervention : Administration of 100mL of 20% Lipid emulsion to all patients in the study group
The control arm The study group was compared with data of patients admitted for OP poisoning between the years 2013 and 2014 ( 2 calendar years), fulfilling the inclusion and exclusion criteria as stated above.