Antibiotics Prior to Mini-screw Implant Insertion
Inflammation at Mini-screw Insertion Site, Mobility, Mini-screw

About this trial
This is an interventional prevention trial for Inflammation at Mini-screw Insertion Site focused on measuring antibiotics, prophylaxis, temporary anchorage devices, mini-screw implants, TADs, MSIs, failure rate
Eligibility Criteria
Inclusion Criteria: Subjects will be selected for the study based on treatment plans for Phase II orthodontics at SLU CADE orthodontics program, which require the use of palatally placed mini-screw implants for anchorage control.
Exclusion Criteria:
- Patients with experience in previous MSI placements
- allergy to amoxicillin
- allergy to Beta-lactam based antibiotics
- medical syndrome diagnoses
- psychiatric disorders (ADHD, autism, manic-depressive disorder, etc.)
- a compromised immune system
- impaired or decreased kidney function
- Type I or Type II diabetes
- patients taking Probenicid or Allopurinol
Sites / Locations
- Saint Louis University Center for Advanced Dental Education
Arms of the Study
Arm 1
Arm 2
Placebo Comparator
Experimental
Control Group
Experimental Group
All participants will be weighed. This group will receive a placebo (glucose) 1 hour prior to insertion of mini-screw implants.
All participants will be weighed so that appropriate dosing can be ensured and will receive 2 grams of Amoxicillin 1 hour prior to mini-screw insertion. Patients weighing less than 40 kg will be given 50mg/kg of Amoxicillin.