Impact of Stigma on Compliance to Medication in Functional Dyspepsia
Functional Gastrointestinal Disorders, Adherence, Patient
About this trial
This is an interventional treatment trial for Functional Gastrointestinal Disorders
Eligibility Criteria
Inclusion Criteria:
- 18-70 years old;
- met the ROME IV criteria for FD;
- absence of abnormalities in physical examination, laboratory tests (including a routine blood test, blood glucose, and liver function examination), abdominal ultrasonography and upper GI endoscopy within 6 months;
- absence of H. pylori infection;
- Generalized Anxiety Disorder Scale (GAD-7) ≥ 1 or Patient Health Questionnaire Depression Scale (PHQ-9) ≥ 5
Exclusion Criteria:
- any evidence of organic digestive diseases;
- other FGIDs such as IBS;
- severe psychological symptoms with GAD-7 ≥ 11 or PHQ-9 ≥15;
- pregnancy or breastfeeding; recent myocardial infarction or cardiac arrhythmias;
- previous gastric surgery;
- use of PPIs, psychoactive drugs or other drugs that might affect gastric function within 6 months
Sites / Locations
- RenJiHRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Other
Other
Other
Other
psychological and GI mechanisms
psychological mechanism
GI mechanism
no explanation
The patients in Group 1 were told that: GI symptoms in FD are attributable to both psychological and GI mechanisms. Psychoactive medicine relieves FD symptoms through both psychological and GI mechanisms.
The patients in Group 2 were told that: GI symptoms in FD are attributable to psychological mechanisms. Psychoactive medicine relieves FD symptoms through psychological mechanisms.
The patients in Group 3 were told that: GI symptoms in FD are attributable to GI mechanisms. Psychoactive medicine relieves FD symptoms through GI mechanisms.
The patients in Group 4 were not explained with the detailed mechanism of FD and psychoactive medicine